Fischer M, Thermann M, Hamelmann H
Chirurg. 1978 Feb;49(2):111-3.
Manometric investigations in patients with primary chronic fissure in ano were performed before and after stretching or sphincterotomy in a randomized clinical trial. Length of the functional anal canal was not influenced by the procedures. At a six-month follow-up, the maximum resting anal pressure was significantly lower in both groups. After stretching and sphincterotomy, the site of maximum pressure in the anal canal had moved orally. This demonstrates that an elevated resting anal pressure is one of the pathogenetic mechanisms for the development of a primary chronic fissure. It is successfully cut off by either stretching or sphincterotomy.
在一项随机临床试验中，对原发性慢性肛裂患者在进行肛管扩张或括约肌切开术前后进行了测压研究。肛管功能长度不受这些手术的影响。在六个月的随访中，两组患者的最大静息肛管压力均显著降低。肛管扩张和括约肌切开术后，肛管内最大压力部位向上移动。这表明静息肛管压力升高是原发性慢性肛裂发生的致病机制之一。通过肛管扩张或括约肌切开术可成功消除这一致病机制。
