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石榴的酚类成分与生物活性

Phenolic Components and Biological Activity of Pomegranate.

作者信息

Zhou Zhiping, Ma Chaoyan, Hao Pengchao, Peng Liyan, Zhang Sophia Yi, Zhao Qinshi

机构信息

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, P. R. China.

Yatsen Global Innovation R&D Center, No. 11 Building, No. 210, Wenshui Road, Jingan District, Shanghai, China.

出版信息

Chem Biodivers. 2025 Mar;22(3):e202402301. doi: 10.1002/cbdv.202402301. Epub 2024 Nov 29.

Abstract

Pomegranate (Punica granatum L.) have been subject of extensive studies for its abundance of phytochemicals and numerous biological and medicinal properties. It is a fruit-bearing tree, which is widely consumed as a nutraceutical source as well as functional food for putative health benefits. The phenolic components are the characteristic bioactive constitutes of pomegranate, including hydrolysable tannins, flavonoids, and phenolic acids. The whole plant of this tree has many medicinal folkloric uses and good therapeutic effect, such as anticancer, antioxidant, antibacterial, antiviral, hypoglycemic, lipid-lowering, cardioprotection and digestive system protection. Through comprehensive search of available literature, this narrative review can provide an up-to-date overview of the current knowledge of characteristic bioactive constituents's structure and potential health benefits of Pomegranate, which can be used as reference for the future clinical and basic research, and also helpful for the development of pomegranate into functional food and nutraceuticals.

摘要

石榴(Punica granatum L.)因其丰富的植物化学成分以及众多的生物学和药用特性而受到广泛研究。它是一种结果实的树,作为一种营养保健品来源以及具有潜在健康益处的功能性食品被广泛食用。酚类成分是石榴的特征性生物活性成分,包括可水解单宁、黄酮类化合物和酚酸。这种树的全株有许多民间药用用途且治疗效果良好,如抗癌、抗氧化、抗菌、抗病毒、降血糖、降血脂、心脏保护和消化系统保护。通过全面检索现有文献,本叙述性综述可以提供关于石榴特征性生物活性成分的结构和潜在健康益处的当前知识的最新概述,可为未来的临床和基础研究提供参考,也有助于将石榴开发成功能性食品和营养保健品。

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