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儿童哮喘患病率与食物污染物膳食暴露之间的关联:CHASER研究。

Associations between the prevalence of asthma and dietary exposure to food contaminants in children: CHASER study.

作者信息

Hinojosa-Nogueira Daniel, Dello Russo Marika, Navajas-Porras Beatriz, Delgado-Osorio Adriana, Pérez-Burillo Sergio, La Grutta Stefania, Cilluffo Giovanna, Malizia Velia, de la Cueva Silvia Pastoriza, Lauria Fabio, Rufián-Henares José Ángel

机构信息

Department of Nutrition and Food Science, Institute of Nutrition and Food Technology, Biomedical Research Centre, University of Granada, 18071, Granada, Spain.

Institute of Food Sciences, National Research Council, 83100, Avellino, Italy.

出版信息

World J Pediatr. 2024 Dec;20(12):1240-1248. doi: 10.1007/s12519-024-00849-4. Epub 2024 Nov 13.

DOI:10.1007/s12519-024-00849-4
PMID:39532762
Abstract

BACKGROUND

Asthma is a common, multifactorial chronic disease with a major impact on children and adolescents. Exposure to food contaminants is one of the contributing factors to asthma. This study aims to evaluate the intake and exposure of different contaminants and explore their association with childhood asthma.

METHODS

The Childhood Asthma and Environment Research study evaluated Italian children aged 5-14 years, divided into control and asthma case groups. Dietary habits were recorded, and exposure to 11 food contaminants was estimated with the CONT11 database. The study included 428 children, 264 with asthma and 164 without.

RESULTS

The findings of this study were consistent with those reported in other studies, indicating that exposure to nitrates and acrylamide was significantly higher in asthmatic children. The results suggest that exposure to certain contaminants could have a more pronounced effect on asthmatic children.

CONCLUSIONS

The study demonstrates the importance of tools such as CONT11 in assessing food safety. Furthermore, it reinforces the need to prevent and reduce exposure to food contaminants to minimize health risks.

摘要

背景

哮喘是一种常见的多因素慢性疾病,对儿童和青少年有重大影响。接触食物污染物是导致哮喘的因素之一。本研究旨在评估不同污染物的摄入量和暴露情况,并探讨它们与儿童哮喘的关联。

方法

儿童哮喘与环境研究对5至14岁的意大利儿童进行了评估,分为对照组和哮喘病例组。记录饮食习惯,并使用CONT11数据库估计对11种食物污染物的暴露情况。该研究包括428名儿童,其中264名患有哮喘,164名没有哮喘。

结果

本研究的结果与其他研究报告的结果一致,表明哮喘儿童中硝酸盐和丙烯酰胺的暴露量明显更高。结果表明,接触某些污染物可能对哮喘儿童有更显著的影响。

结论

该研究证明了CONT11等工具在评估食品安全方面的重要性。此外,它强化了预防和减少食物污染物暴露以将健康风险降至最低的必要性。

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World J Pediatr. 2024 Dec;20(12):1240-1248. doi: 10.1007/s12519-024-00849-4. Epub 2024 Nov 13.
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本文引用的文献

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Prenatal dietary exposure to chemicals and allergy or respiratory diseases in children in the EDEN mother-child cohort.EDEN母婴队列研究中儿童产前饮食接触化学物质与过敏或呼吸道疾病的关系
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Pediatr Allergy Immunol. 2023 Jul;34(7):e13984. doi: 10.1111/pai.13984.
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Development of a food composition database of different food contaminants CONT11 and estimation of dietary exposure in children of southern Spain.
不同食品污染物 CONT11 的食品成分数据库的开发及西班牙南部儿童膳食暴露评估。
Food Chem Toxicol. 2023 Jul;177:113843. doi: 10.1016/j.fct.2023.113843. Epub 2023 May 23.
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Estimated Dietary and Health Impact of the World Health Organization's Global Sodium Benchmarks on Packaged Foods in Australia: a Modeling Study.世界卫生组织全球钠基准对澳大利亚包装食品的饮食和健康影响评估:建模研究。
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Vitamin D and Healthcare Service Utilization in Children: Insights from a Machine Learning Approach.维生素D与儿童医疗服务利用:机器学习方法的见解
J Clin Med. 2022 Dec 1;11(23):7157. doi: 10.3390/jcm11237157.
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Obesity-related asthma in children and adolescents.儿童和青少年肥胖相关性哮喘。
Lancet Child Adolesc Health. 2022 Oct;6(10):713-724. doi: 10.1016/S2352-4642(22)00185-7. Epub 2022 Aug 19.
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Adherence to Dietary Recommendations of 7-Year-Old Children from a Birth Cohort in Friuli Venezia Giulia, Italy.意大利弗留利-威尼斯朱利亚某出生队列中7岁儿童对饮食建议的依从性
Nutrients. 2022 Jan 25;14(3):515. doi: 10.3390/nu14030515.
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Primary Prevention of Pediatric Asthma through Nutritional Interventions.通过营养干预预防儿童哮喘
Nutrients. 2022 Feb 10;14(4):754. doi: 10.3390/nu14040754.
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Effects of Polycyclic Aromatic Hydrocarbons on Lung Function in Children with Asthma: A Mediation Analysis.多环芳烃对哮喘患儿肺功能的影响:中介分析。
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Association between Asthma Control and Exposure to Greenness and Other Outdoor and Indoor Environmental Factors: A Longitudinal Study on a Cohort of Asthmatic Children.哮喘控制与暴露于绿化及其他室外和室内环境因素之间的关联:对哮喘患儿队列进行的一项纵向研究。
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