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儿童哮喘患病率与食物污染物膳食暴露之间的关联:CHASER研究。

Associations between the prevalence of asthma and dietary exposure to food contaminants in children: CHASER study.

作者信息

Hinojosa-Nogueira Daniel, Dello Russo Marika, Navajas-Porras Beatriz, Delgado-Osorio Adriana, Pérez-Burillo Sergio, La Grutta Stefania, Cilluffo Giovanna, Malizia Velia, de la Cueva Silvia Pastoriza, Lauria Fabio, Rufián-Henares José Ángel

机构信息

Department of Nutrition and Food Science, Institute of Nutrition and Food Technology, Biomedical Research Centre, University of Granada, 18071, Granada, Spain.

Institute of Food Sciences, National Research Council, 83100, Avellino, Italy.

出版信息

World J Pediatr. 2024 Dec;20(12):1240-1248. doi: 10.1007/s12519-024-00849-4. Epub 2024 Nov 13.

Abstract

BACKGROUND

Asthma is a common, multifactorial chronic disease with a major impact on children and adolescents. Exposure to food contaminants is one of the contributing factors to asthma. This study aims to evaluate the intake and exposure of different contaminants and explore their association with childhood asthma.

METHODS

The Childhood Asthma and Environment Research study evaluated Italian children aged 5-14 years, divided into control and asthma case groups. Dietary habits were recorded, and exposure to 11 food contaminants was estimated with the CONT11 database. The study included 428 children, 264 with asthma and 164 without.

RESULTS

The findings of this study were consistent with those reported in other studies, indicating that exposure to nitrates and acrylamide was significantly higher in asthmatic children. The results suggest that exposure to certain contaminants could have a more pronounced effect on asthmatic children.

CONCLUSIONS

The study demonstrates the importance of tools such as CONT11 in assessing food safety. Furthermore, it reinforces the need to prevent and reduce exposure to food contaminants to minimize health risks.

摘要

背景

哮喘是一种常见的多因素慢性疾病,对儿童和青少年有重大影响。接触食物污染物是导致哮喘的因素之一。本研究旨在评估不同污染物的摄入量和暴露情况,并探讨它们与儿童哮喘的关联。

方法

儿童哮喘与环境研究对5至14岁的意大利儿童进行了评估,分为对照组和哮喘病例组。记录饮食习惯,并使用CONT11数据库估计对11种食物污染物的暴露情况。该研究包括428名儿童,其中264名患有哮喘,164名没有哮喘。

结果

本研究的结果与其他研究报告的结果一致,表明哮喘儿童中硝酸盐和丙烯酰胺的暴露量明显更高。结果表明,接触某些污染物可能对哮喘儿童有更显著的影响。

结论

该研究证明了CONT11等工具在评估食品安全方面的重要性。此外,它强化了预防和减少食物污染物暴露以将健康风险降至最低的必要性。

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