Blaxter Mark L, Leech Chloe, Lunt David H
Tree of Life, Wellcome Sanger Institute, Hinxton, England, UK.
Biological Sciences, School of Natural Sciences, University of Hull, Hull, England, UK.
Wellcome Open Res. 2024 Feb 19;9:55. doi: 10.12688/wellcomeopenres.20550.1. eCollection 2024.
Nematodes are important biological models in genetics and genomics, with research driven by basic biological as well as applied questions. The presence of holocentric chromosomes, clades with frequent polyploidy and the phenomenon of programmed DNA elimination make nematode karyotypic diversity of particular interest. Here we present a catalogue of published karyotypes of nematode species, rationalising and normalising descriptions from the previous 135 years. Karyotypes of 257 species are presented in taxonomic context. Nuclear chromosome counts range from 2 to 60. Tylenchina is identified as particularly diverse in karyotype. We highlight that Rhabditida and especially parasitic Rhabditina are well-represented, but there is a paucity of data from Enoplea, Dorylaimia, and from free-living marine groups in Chromadorea. The data have been uploaded to the Genomes on a Tree (GoaT) datasystem ( https://goat.genomehubs.org/) for integration with ongoing, large-scale genome sequencing efforts.
线虫是遗传学和基因组学中重要的生物学模型,其研究由基础生物学问题和应用问题驱动。全着丝粒染色体的存在、频繁出现多倍体的进化枝以及程序性DNA消除现象,使得线虫核型多样性格外引人关注。在此,我们呈现了一份已发表的线虫物种核型目录,对过去135年的描述进行了梳理和规范。257个物种的核型按分类学背景列出。核染色体数从2到60不等。垫刃总科被确定为核型特别多样的类群。我们强调小杆目,尤其是寄生性小杆亚目有充分的代表性,但色矛纲中的刺嘴目、矛线目以及自由生活的海洋类群的数据匮乏。这些数据已上传至“树上的基因组”(GoaT)数据系统(https://goat.genomehubs.org/),以便与正在进行的大规模基因组测序工作整合。