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采用纳秒激光烧蚀绿色方法提高掺银纳米颗粒的 PVC/PVDF 薄膜的抗菌性能,应用于伤口愈合。

A green approach to improve antibacterial properties of PVC/PVDF film doped by silver nanoparticles via nanosecond laser ablation for wound healing application.

机构信息

Chemistry Department, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt.

Department of Physics, Faculty of Science, Suez University, Suez, 43518, Egypt.

出版信息

Sci Rep. 2024 Nov 13;14(1):27926. doi: 10.1038/s41598-024-78841-1.

Abstract

Nanocomposite films of (30% PVC/70% PVDF) blend containing silver nanoparticles were synthesized via pulsed laser ablation route (PLA). Changes in physical characterization of PVC/PVDF blend before and after the incorporation of AgNPs have been studied. FTIR results confirms the interaction between AgNPs and PVC/PVDF. XRD results obtain the existence of peak at 38.42̊ in sample PVC/PVDF/Ag4 which confirm the embedded AgNPs in the high concentration. SEM photos confirm the distribution of silver nanoparticles on the surface of the sample in spherical shape which approved the dispersion of silver nanoparticles in PVC/PVDF blend. The inhibitory zone diameters observed for PVC/PVDF/Ag4 against Escherichia coli, Klebsiella pneumonia, Staphylococcus aureus, and Bacillus cereus were recorded as 11 ± 1, 10 ± 1, 15.7 ± 0.6, and 17.7 ± 0.6, respectively. PVC/PVDF/AgNPs nanocomposite film could be suggested for biomedical applications such as wound healing products.

摘要

(30% PVC/70% PVDF)共混物的含银纳米粒子的纳米复合膜通过脉冲激光烧蚀法(PLA)合成。研究了在掺入 AgNPs 前后 PVC/PVDF 共混物的物理特性变化。FTIR 结果证实了 AgNPs 与 PVC/PVDF 之间的相互作用。XRD 结果在样品 PVC/PVDF/Ag4 中获得了 38.42̊处的峰的存在,证实了高浓度下嵌入的 AgNPs。SEM 照片证实了银纳米粒子在样品表面呈球形分布,这证实了银纳米粒子在 PVC/PVDF 共混物中的分散性。观察到的 PVC/PVDF/Ag4 对大肠杆菌、肺炎克雷伯菌、金黄色葡萄球菌和蜡状芽孢杆菌的抑菌圈直径分别为 11±1、10±1、15.7±0.6 和 17.7±0.6。可以建议将 PVC/PVDF/AgNPs 纳米复合膜用于生物医学应用,例如伤口愈合产品。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba3f/11561074/e885961a78fe/41598_2024_78841_Fig2_HTML.jpg

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