Liu Ziping, Zhang Zelin, Xie Ping
College of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Department of Gynecology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Front Med (Lausanne). 2024 Oct 30;11:1465893. doi: 10.3389/fmed.2024.1465893. eCollection 2024.
In recent years, extensive research has been conducted on endometrial receptivity (ER), with rapidly evolving research hotspots and trends. Our study aimed to explore the development of ER research from 2000 to the present and provide insights for future endeavors.
Relevant research publications on ER from 2000 to 2024 were retrieved from the Web of Science Core Collection (WOSCC) database. CiteSpace, VOSviewer and Excel tools were employed to conduct the bibliometric analysis.
A total of 3,354 articles were analyzed, revealing an overall upward trend in annual publication numbers, signifying the increasing attractiveness and research value of this field. Globally, China led with a notable advantage of 1,030 publications, followed by the United States (650) and Spain (251), constituting the first tier of international research. Valencia University topped the list of institutions with 108 publications, closely followed by Shanghai Jiao Tong University with 87. (IF6.6, Q1) is the one with the largest number of publications, accounting for 7.96% of the total publications. The three most co-cited journals were , , and . A co-citation reference analysis revealed that ER research can be categorized into ten major subfields, including embryo implantation, frozen embryo transfer, integrins, recurrent implantation failure, intrauterine adhesions, etc. Since 2020, the keywords with the strongest citation bursts include repeated implantation failure and frozen.
This study employs bibliometric analysis to offer researchers in the field of ER a comprehensive perspective. Since 2000, there has been a remarkable surge in the number of publications in the ER research field. These studies primarily concentrate on delving into the pathophysiological mechanisms of ER, with the primary objective of enhancing clinical pregnancy rates and live birth rates, benefiting more infertile patients. Currently, addressing the ER issues in patients with recurrent implantation failure represents the forefront of research. The primary treatment approaches currently in use involve optimizing embryo transfer timing and employing innovative strategies such as immunotherapy. These cutting-edge analyses not only provide new insights into the treatment of ER but also offer researchers fresh research directions, and staying abreast of the latest trends and advancements in the field.
近年来，关于子宫内膜容受性（ER）的研究广泛开展，研究热点和趋势迅速演变。我们的研究旨在探讨2000年至今ER研究的发展情况，并为未来的研究提供见解。
从Web of Science核心合集（WOSCC）数据库中检索2000年至2024年关于ER的相关研究出版物。使用CiteSpace、VOSviewer和Excel工具进行文献计量分析。
共分析了3354篇文章，年度发表数量总体呈上升趋势，表明该领域的吸引力和研究价值在不断增加。在全球范围内，中国以1030篇出版物的显著优势位居榜首，其次是美国（650篇）和西班牙（251篇），构成国际研究的第一梯队。瓦伦西亚大学以108篇出版物位居机构榜首，紧随其后的是上海交通大学，有87篇。（IF6.6，Q1）是发表数量最多的期刊，占总出版物的7.96%。被共同引用最多的三种期刊是 、 和 。共引参考文献分析表明，ER研究可分为十个主要子领域，包括胚胎着床、冷冻胚胎移植、整合素、反复着床失败、宫腔粘连等。自2020年以来，引用爆发最强的关键词包括反复着床失败和冷冻。
本研究采用文献计量分析为ER领域的研究人员提供了全面的视角。自2000年以来，ER研究领域的出版物数量显著激增。这些研究主要集中在深入探究ER的病理生理机制，主要目标是提高临床妊娠率和活产率，使更多不孕患者受益。目前，解决反复着床失败患者的ER问题是研究的前沿。目前使用的主要治疗方法包括优化胚胎移植时机和采用免疫治疗等创新策略。这些前沿分析不仅为ER的治疗提供了新的见解，也为研究人员提供了新的数据研究方向，并紧跟该领域的最新趋势和进展。
