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[膈肌移动时间指数作为重症治疗中拔管预测指标的研究]

[Diaphragmatic excursion time index as a predictor of extubation in intensive therapy].

作者信息

Domínguez-Estrada Salvador, Bravo-Santibañez Edgar, Ramos-Ramos Xóchitl, López-Briones José-Sergio

机构信息

Instituto Mexicano del Seguro Social, Hospital Regional No. 58, Servicio de Terapia Intensiva. León, Guanajuato, México.

Instituto Mexicano del Seguro Social, Unidad Médica de Alta Especialidad No. 1 Bajío, Servicio de Terapia Intensiva. León, Guanajuato, México.

出版信息

Rev Med Inst Mex Seguro Soc. 2024 Jul 1;62(4):1-7. doi: 10.5281/zenodo.11396976.

Abstract

BACKGROUND

Extubation is a critical process in the ICU. Pulmonary USG has different applications, those that predict success in extubation, such as the diaphragmatic excursion time index (DEIT).

OBJECTIVE

To determine the diaphragmatic excursion time index is a predictor of the success of weaning off mechanical ventilation in patients in the intensive care unit.

MATERIAL AND METHODS

Diagnostic performance study in patients in the ICU and in the extubation protocol. Diaphragmatic measurement by USG, evaluating DEIT; cut-off point of 2.42 ± 1.55 cm/s. In the hypothesis test, a JI square was carried out between the two qualitative variables, in order to accept or reject H0, with a statistical significance of p < 0.05 to determine if there is dependence between the dependent and independent variables.

RESULTS

Total of 200 patients from the population, with successful extubation in 52.5% and extubation failure in 47.5%. Prognostic values of the DEIT were: S: 77.1% (68.2-84.1%), E: 56.8% (46.8-66.3%). ROC curve for ITED, AUC of 0.665 (0.58-0.74; p = 0.001). In secondary objectives, a correlation was made between ventilatory and demographic variables for successful extubation; with FvT (Rho: 0.680, p = 0.0001).

CONCLUSIONS

The DEIT for withdrawal of mechanical ventilation has low sensitivity and specificity as a result of successful extubation. The finding that DEIT is not an adequate predictor determining the outcome of successful extubation.

摘要

背景

拔管是重症监护病房(ICU)中的关键环节。肺部超声有不同的应用,其中一些可预测拔管成功与否,如膈肌移动时间指数(DEIT)。

目的

确定膈肌移动时间指数是否可预测重症监护病房患者机械通气撤机的成功与否。

材料与方法

对ICU患者及拔管方案进行诊断性能研究。通过超声测量膈肌,评估DEIT;截断点为2.42±1.55cm/s。在假设检验中,对两个定性变量进行卡方检验,以接受或拒绝H0,显著性水平为p<0.05,以确定因变量和自变量之间是否存在相关性。

结果

研究人群共200例患者,拔管成功52.5%,拔管失败47.5%。DEIT的预测值为:敏感度(S):77.1%(68.2 - 84.1%),特异度(E):56.8%(46.8 - 66.3%)。DEIT的ROC曲线,曲线下面积(AUC)为0.665(0.58 - 0.74;p = 0.001)。在次要目标中,对成功拔管的通气和人口统计学变量进行了相关性分析;与用力肺活量(FvT)相关(Rho:0.680,p = 0.0001)。

结论

作为拔管成功的指标,机械通气撤机的DEIT敏感度和特异度较低。研究发现DEIT并非确定拔管成功结果的充分预测指标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ff2/12324816/cfeb71ebcb26/04435117-62-4-e6000-c001.jpg

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