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停止机械通气支持。

Discontinuing mechanical ventilatory support.

作者信息

MacIntyre Neil

机构信息

Duke University Medical Center, Durham, NC 27710, USA.

出版信息

Chest. 2007 Sep;132(3):1049-56. doi: 10.1378/chest.06-2862.

Abstract

The ventilator discontinuation process is a critical component of ICU care. Ongoing ventilator dependency is caused by both disease factors (eg, respiratory, cardiac, metabolic, and neuromuscular) and clinician management factors (eg, failing to recognize discontinuation potential and inappropriate ventilator settings/management). A multispecialty evidence-based task force has recommended a series of guidelines that begins with a daily ventilator weaning screen focusing on disease stability/recovery, gas exchange, hemodynamics, and respiratory drive that should be done on every patient receiving mechanical ventilatory support. In those passing this screen, a spontaneous breathing trial (SBT) should be performed. The decision to remove the artificial airway in those patients successfully passing an SBT requires further assessment of the patient's ability to protect the airway. Managing the patient who fails the SBT is one of the biggest challenges facing ICU clinicians. In general, stable, comfortable modes of assisted/supported ventilatory support should be provided between the daily weaning screen/SBT. New evidence suggests that early tracheostomy placement may facilitate the ventilator withdrawal process in those patients requiring prolonged ventilatory support.

摘要

撤机过程是重症监护病房(ICU)护理的关键组成部分。持续依赖呼吸机是由疾病因素(如呼吸、心脏、代谢和神经肌肉疾病)和临床医生管理因素(如未认识到撤机可能性以及不适当的呼吸机设置/管理)共同导致的。一个多专业循证工作组推荐了一系列指南,该指南从每日呼吸机撤机筛查开始,重点关注疾病稳定性/恢复情况、气体交换、血流动力学和呼吸驱动,应对每一位接受机械通气支持的患者进行此项筛查。对于通过该筛查的患者,应进行自主呼吸试验(SBT)。对于成功通过SBT的患者,决定移除人工气道需要进一步评估患者保护气道的能力。处理未通过SBT的患者是ICU临床医生面临的最大挑战之一。一般而言,在每日撤机筛查/SBT之间应提供稳定、舒适的辅助/支持通气模式。新证据表明,对于需要长期通气支持的患者,早期气管切开术可能有助于撤机过程。

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