• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

原发性肺癌（EORTC-1901）：小细胞肺癌（SCLC）患者的预防性脑照射（PCI）或主动脑部磁共振成像（MRI）监测

PRIMALung (EORTC-1901): PRophylactic cerebral irradiation (PCI) or active brain MAgnetic resonance imaging (MRI) surveillance in small-cell lung cancer (SCLC) patients.

作者信息

Levy Antonin, Berghmans Thierry, Koller Michael, Fournier Beatrice, Mauer Murielle, Andratschke Nicolaus, Faivre-Finn Corinne

机构信息

Department of Radiation Oncology, Gustave Roussy, Villejuif, France; Gustave Roussy, Inserm U1030, Université Paris-Saclay, Villejuif, France; Faculté de Médecine, Université Paris Saclay, Le Kremlin-Bicêtre, France.

Thoracic Oncology, Institut Jules Bordet, Hôpital Universitaire de Bruxelles, Université Libre de Bruxelles (ULB), Brussels, Belgium.

出版信息

Lung Cancer. 2024 Dec;198:107993. doi: 10.1016/j.lungcan.2024.107993. Epub 2024 Oct 24.

DOI:10.1016/j.lungcan.2024.107993
PMID:39541773
Abstract

The PRIMALung EORTC-1901 trial investigates brain MRI ± PCI in all-stages of SCLC, aiming for non-inferior survival, improve cognition in the era of immunotherapy. @finn_corinne.

摘要

PRIMALung EORTC-1901试验在小细胞肺癌的各个阶段研究脑部MRI±全脑放疗，目标是获得非劣效生存期，在免疫治疗时代改善认知。@finn_corinne

相似文献

1
PRIMALung (EORTC-1901): PRophylactic cerebral irradiation (PCI) or active brain MAgnetic resonance imaging (MRI) surveillance in small-cell lung cancer (SCLC) patients.原发性肺癌（EORTC-1901）：小细胞肺癌（SCLC）患者的预防性脑照射（PCI）或主动脑部磁共振成像（MRI）监测
Lung Cancer. 2024 Dec;198:107993. doi: 10.1016/j.lungcan.2024.107993. Epub 2024 Oct 24.
2
Effects of brain radiotherapy strategies on survival in the era of MRI for patients with limited stage small cell lung cancer.脑放疗策略对 MRI 时代局限期小细胞肺癌患者生存的影响。
BMC Cancer. 2024 Aug 5;24(1):953. doi: 10.1186/s12885-024-12739-z.
3
Rates of Overall Survival and Intracranial Control in the Magnetic Resonance Imaging Era for Patients With Limited-Stage Small Cell Lung Cancer With and Without Prophylactic Cranial Irradiation.限局性小细胞肺癌患者接受和未接受预防性颅脑照射的磁共振成像时代的总生存和颅内控制率。
JAMA Netw Open. 2020 Apr 1;3(4):e201929. doi: 10.1001/jamanetworkopen.2020.1929.
4
Outcomes of prophylactic cranial irradiation in patients with small cell lung cancer in the modern era of baseline magnetic resonance imaging of the brain.在现代基线脑部磁共振成像时代，小细胞肺癌患者预防性颅脑照射的结果。
Acta Oncol. 2022 Feb;61(2):185-192. doi: 10.1080/0284186X.2021.1974553. Epub 2021 Sep 28.
5
Current Patterns of Care for Patients with Extensive-Stage SCLC: Survey of U.S. Radiation Oncologists on Their Recommendations Regarding Prophylactic Cranial Irradiation.广泛期小细胞肺癌患者的治疗现状：对美国放疗医师关于预防性颅脑照射推荐意见的调查。
J Thorac Oncol. 2016 Aug;11(8):1305-1310. doi: 10.1016/j.jtho.2016.04.031. Epub 2016 May 26.
6
Efficacy of Prophylactic Cranial Irradiation in Early to Mid-stage Small Cell Lung Cancer Patients in the Era of Magnetic Resonance Imaging.早期至中期小细胞肺癌患者预防性全脑照射的疗效在磁共振成像时代。
Clin Lung Cancer. 2024 Dec;25(8):690-698.e2. doi: 10.1016/j.cllc.2024.08.005. Epub 2024 Aug 13.
7
Survival impact of prophylactic cranial irradiation in small-cell lung cancer in the modern era of magnetic resonance imaging staging.在现代磁共振成像分期时代，预防性颅脑照射对小细胞肺癌的生存影响。
Radiat Oncol. 2022 Feb 5;17(1):26. doi: 10.1186/s13014-022-01994-8.
8
The impact of Prophylactic cranial irradiation on the prognosis of patients with limited-stage small cell lung cancer in the MRI era.预防性颅照射对 MRI 时代局限期小细胞肺癌患者预后的影响。
Radiat Oncol. 2024 Nov 14;19(1):162. doi: 10.1186/s13014-024-02557-9.
9
Prophylactic Cranial Irradiation for Patients With SCLC-A New Perspective in the Immunotherapy Era.小细胞肺癌患者的预防性颅脑照射——免疫治疗时代的新视角
J Thorac Oncol. 2025 Mar;20(3):395-398. doi: 10.1016/j.jtho.2024.11.011. Epub 2024 Nov 15.
10
Prophylactic Cranial Irradiation (PCI) versus Active MRI Surveillance for Small Cell Lung Cancer: The Case for Equipoise.预防性全脑照射（PCI）与小细胞肺癌主动 MRI 监测的比较：均衡观点。
J Thorac Oncol. 2017 Dec;12(12):1746-1754. doi: 10.1016/j.jtho.2017.08.016. Epub 2017 Sep 4.

引用本文的文献

1
An effective flowchart for multimodal brain tumor binary classification with ranked 3D texture features.一种用于具有排名三维纹理特征的多模态脑肿瘤二元分类的有效流程图。
Sci Rep. 2025 Aug 20;15(1):30531. doi: 10.1038/s41598-025-11240-2.
2
Efficacy evaluation of prophylactic cranial irradiation for limited stage small‑cell lung cancer in the magnetic resonance imaging era: A meta‑analysis.磁共振成像时代预防性颅脑照射对局限期小细胞肺癌的疗效评估：一项荟萃分析
Oncol Lett. 2025 Jan 7;29(3):123. doi: 10.3892/ol.2025.14870. eCollection 2025 Mar.
3
First-Line Chemo-Immunotherapy in SCLC: Outcomes of a Binational Real-World Study.
小细胞肺癌的一线化疗免疫疗法：一项双边真实世界研究的结果
JTO Clin Res Rep. 2024 Oct 17;6(1):100744. doi: 10.1016/j.jtocrr.2024.100744. eCollection 2025 Jan.
4
Prophylactic cranial irradiation in small cell lung cancer: A review of evidence.小细胞肺癌的预防性颅脑照射：证据综述
J Biomed Res. 2025 Jan 25;39(2):1-4. doi: 10.7555/JBR.38.20240293.
5
Advances in the Management of Lung Cancer Brain Metastases.肺癌脑转移的治疗进展
Cancers (Basel). 2024 Nov 9;16(22):3780. doi: 10.3390/cancers16223780.
6
Rational and design of prophylactic cranial irradiation (PCI) and brain MRI surveillance versus brain MRI surveillance alone in patients with limited-stage small cell lung cancer achieving complete remission (CR) of tumor after chemoradiotherapy: a multicenter prospective randomized study.化放疗后达到完全缓解的局限期小细胞肺癌患者预防性颅脑照射（PCI）与单纯脑 MRI 监测的合理选择和设计：一项多中心前瞻性随机研究。
BMC Cancer. 2024 Apr 8;24(1):429. doi: 10.1186/s12885-024-12123-x.