Dias André Henrique, Andersen Kim Francis, Fosbøl Marie Øbro, Gormsen Lars Christian, Andersen Flemming Littrup, Munk Ole Lajord
Department of Nuclear Medicine and PET-Centre, Aarhus University Hospital, Aarhus, Denmark.
Department of Clinical Physiology and Nuclear Medicine, Rigshospitalet, Copenhagen, Denmark.
Semin Nucl Med. 2025 Jan;55(1):76-85. doi: 10.1053/j.semnuclmed.2024.10.007. Epub 2024 Nov 13.
The combined use of Positron Emission Tomography (PET) and Computed Tomography (CT) has become increasingly vital for diagnosing and managing oncological and infectious diseases in pediatric patients. The introduction of long axial field-of-view (LAFOV) PET/CT scanners, also known as "Total Body PET/CT," marks a significant advancement in nuclear medicine. This new technology enables faster pediatric imaging with substantially reduced radiation exposure and essentially eliminates the need for sedation, addressing previous critical concerns in pediatric imaging. This review will explore the applications and challenges of LAFOV PET/CT in pediatric imaging, highlight the benefits observed at two Danish hospitals, and evaluate its potential to transform the management of pediatric patients.
正电子发射断层扫描（PET）与计算机断层扫描（CT）的联合使用对于诊断和管理儿科患者的肿瘤和传染病变得越来越重要。长轴视野（LAFOV）PET/CT扫描仪的引入，也被称为“全身PET/CT”，标志着核医学的一项重大进展。这项新技术能够实现更快的儿科成像，大幅减少辐射暴露，基本上消除了镇静的必要性，解决了之前儿科成像中的关键问题。本综述将探讨LAFOV PET/CT在儿科成像中的应用和挑战，突出在两家丹麦医院观察到的益处，并评估其改变儿科患者管理的潜力。
