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[急性社区获得性细菌性脑膜炎的管理:意识障碍和发热伴/不伴头痛的主要症状]

[Management of acute community-acquired bacterial meningitis : Leading symptoms of impaired consciousness and fever with/without headache].

作者信息

Dyckhoff-Shen Susanne, Klein Matthias

机构信息

Neurologische Klinik und Poliklinik, Ludwig-Maximilians-Universität (LMU) Klinikum Campus Großhadern, Marchioninistr. 15, 81377, München, Deutschland.

出版信息

Med Klin Intensivmed Notfmed. 2025 Mar;120(2):97-102. doi: 10.1007/s00063-024-01210-3. Epub 2024 Nov 14.

Abstract

BACKGROUND

Simultaneous symptoms of impaired consciousness and fever are suspicious for acute bacterial meningitis. This is a medical emergency and prompt action is essential.

OBJECTIVES

The clinical workup for suspected bacterial meningitis as well as treatment recommendations and differential diagnosis for the main symptoms of decreased vigilance and fever are described.

METHODS

Evaluation of selective literature using PubMed (U.S. National Library of Medicine®, Bethesda, MD, USA), especially taking into account the AWMF (Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften) guideline of community-acquired bacterial meningoencephalitis in adults.

RESULTS

Bacterial meningoencephalitis presents with the main symptoms of impaired consciousness, nuchal rigidity, headache and fever, which may, however, be absent in some cases. The diagnosis is confirmed by investigation of the cerebrospinal fluid. Further diagnostics include emergency laboratory tests, blood cultures, microbiological examinations, and cranial computed tomography (CCT). Empirical treatment should be administered promptly.

CONCLUSION

Acute bacterial meningitis must be considered in cases of loss of vigilance and fever, requiring a rapid, structured approach in the emergency department.

摘要

背景

意识障碍和发热同时出现的症状怀疑为急性细菌性脑膜炎。这是一种医疗急症,必须迅速采取行动。

目的

描述疑似细菌性脑膜炎的临床检查以及对警觉性降低和发热等主要症状的治疗建议和鉴别诊断。

方法

使用美国国立医学图书馆(位于美国马里兰州贝塞斯达)的PubMed对相关文献进行筛选评估,尤其参考了德国医学专业学会协作组织(AWMF)关于成人社区获得性细菌性脑膜脑炎的指南。

结果

细菌性脑膜脑炎的主要症状为意识障碍、颈项强直、头痛和发热,但在某些情况下可能不存在这些症状。通过脑脊液检查确诊。进一步的诊断包括急诊实验室检查、血培养、微生物学检查和头颅计算机断层扫描(CCT)。应立即进行经验性治疗。

结论

在出现警觉性丧失和发热的情况下必须考虑急性细菌性脑膜炎,在急诊科需要采取快速、有条理的方法。

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