Tao Zihao, Qiu Yongkang, Chen Zhao, Huang Wenpeng, Song Lele, Wang Aixiang, Li Xuesong, Kang Lei
Department of Nuclear Medicine, Peking University First Hospital, Beijing, 100034, China.
Department of Urology, Institute of Urology, Peking University First Hospital, Peking University, National Urological Cancer Center, Beijing, 100034, China.
EJNMMI Res. 2024 Nov 14;14(1):109. doi: 10.1186/s13550-024-01177-4.
Primary mesenchymal tumors of the prostate are very rare, and there is no systematic report on fluorine-18-fluorodeoxyglucose positron emission tomography (F-FDG PET/CT). The aim of this research was to characterize mesenchymal tumors of the prostate on F-FDG PET/CT.
We included 13 patients with pathologically confirmed mesenchymal neoplasms of the prostate. The location, size, maximum standardized uptake value (SUVmax), metabolic tumor volume (MTV), total glycolysis of the lesion (TLG), pathologic findings, and available imaging study of the tumors were reviewed. Of the 13 patients (median age, 38 years; ranged from 13 to 74 years), the mean size of the tumors was 8.8 cm in diameter ranged from 5 to 16.1 cm. SUVmax ranged from 3.1 to 17.6 (mean 9.5), MTV ranged from 4.9 to 398 cm (mean 109 cm) and TLG ranged from 21.3 to 1216 g (mean 96 g). The seminal vesicles, rectum, and bladder are the most commonly affected sites of invasion, while metastasis typically occurs in the bones, lungs, and lymph nodes.
Mesenchymal tumors of the prostate revealed large sizes and high SUVmax, MTV and TLG levels on F-FDG PET/CT. F-FDG PET/CT may be useful for accurate diagnosis, staging, and restaging, which plays an important role in the management of subsequent plans.
前列腺原发性间叶肿瘤非常罕见，目前尚无关于氟-18-氟脱氧葡萄糖正电子发射断层扫描（F-FDG PET/CT）的系统报道。本研究的目的是在F-FDG PET/CT上对前列腺间叶肿瘤进行特征描述。
我们纳入了13例经病理证实的前列腺间叶肿瘤患者。回顾了肿瘤的位置、大小、最大标准化摄取值（SUVmax）、代谢肿瘤体积（MTV）、病变的总糖酵解（TLG）、病理结果以及可用的影像学研究。13例患者（中位年龄38岁；年龄范围为13至74岁），肿瘤平均直径为8.8 cm，范围为5至16.1 cm。SUVmax范围为3.1至17.6（平均9.5），MTV范围为4.9至398 cm（平均109 cm），TLG范围为21.3至1216 g（平均96 g）。精囊、直肠和膀胱是最常受侵犯的部位，而转移通常发生在骨骼、肺和淋巴结。
前列腺间叶肿瘤在F-FDG PET/CT上显示出较大的尺寸以及较高的SUVmax、MTV和TLG水平。F-FDG PET/CT可能有助于准确诊断、分期和再分期，在后续治疗计划的制定中发挥重要作用。
