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[急性放射病中组织嗜碱性粒细胞的多变量统计分析]

[Multivariate statistical analysis of tissue basophils in acute radiation sickness].

作者信息

Datsenko A V, Shikhodyrov V V, Korneliuk V A

出版信息

Arkh Anat Gistol Embriol. 1986 Jan;90(1):69-72.

PMID:3954605
Abstract

By means of mark scale estimation method, discriminant and factor analyses, changes in integral indices on the state of mast cells in the rat mesentery have been investigated in dynamics of medullary, intestinal and cerebral forms of an acute radiation sickness. The integral indices are calculated basing on the morphometric parameters of the cells, that are obtained after the histological preparations are treated in a special automatic system for analysing images. At the medullary form of the acute radiation sickness, the greatest structural rearrangements of the mast cells take place during the first hours after the radiation, as well as during the climax of the disease, at the intestinal form, the analogous changes are revealed 1-3 days after the effect, and at the cerebral form--3 h after the radiation. The integral indices, calculated by means of the three methods, are well correlated with each other.

摘要

通过标记量表估计法、判别分析和因子分析,研究了急性放射病的骨髓型、肠型和脑型病程动态中大鼠肠系膜肥大细胞状态积分指标的变化。积分指标是根据细胞的形态计量学参数计算得出的,这些参数是在组织学标本经特殊图像分析自动系统处理后获得的。在急性放射病的骨髓型中,肥大细胞最大的结构重排在照射后的最初数小时以及疾病高峰期发生;在肠型中,类似变化在照射后1 - 3天出现;在脑型中,则在照射后3小时出现。通过三种方法计算出的积分指标彼此相关性良好。

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