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[急性放射病大鼠肠系膜淋巴床的病理学]

[Pathology of the rat mesenteric lymphatic bed in acute radiation sickness].

作者信息

Datsenko A V, Shikhodyrov V V

出版信息

Med Radiol (Mosk). 1985 Feb;30(2):39-43.

PMID:3969003
Abstract

The authors have shown that in the medullary, intestinal and cerebral forms of acute radiation disease pathological changes of the lymphatic microvessels manifested themselves in the form of lymphostasis at the climax of disease in the medullary form of acute radiation disease and at the climax and in the terminal period in the intestinal form. A characteristic feature of the lymphatic channel involvement in the medullary form of acute radiation disease was a large number of erythrocytes in the lumen of the lymphatic vessels at the climax of disease. No changes of the mesenteric lymphatic channel of the rats were noted in the cerebral form. On the other hand, the presence of a large number of newly formed capillaries in the young rats at the climax of disease indicate the persistence of the proliferative ability of the lymphatic microvessel endothelium and its significant radioresistance.

摘要

作者已经表明,在急性放射病的骨髓型、肠型和脑型中,淋巴微血管的病理变化在急性放射病骨髓型病程高峰期以及肠型病程高峰期和终末期表现为淋巴淤滞。急性放射病骨髓型中淋巴管受累的一个特征是在病程高峰期淋巴管腔内有大量红细胞。脑型中未观察到大鼠肠系膜淋巴管有变化。另一方面,在病程高峰期幼鼠体内存在大量新形成的毛细血管,这表明淋巴微血管内皮细胞的增殖能力持续存在且具有显著的抗辐射性。

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