Paeckel Nico, Zablotski Yury, Meyer-Lindenberg Andrea
Clinic of Small Animal Surgery and Reproduction, Veterinary Faculty, Ludwig-Maximilians-University, Veterinärstr. 13, Munich 80539, Germany.
Vet J. 2024 Dec;308:106267. doi: 10.1016/j.tvjl.2024.106267. Epub 2024 Nov 15.
The aim of this study was to investigate the effect of peri- and postoperative antimicrobial prophylaxis (AMP) on surgical site infection (SSI) in surgeries with elective antibiotic administration in a large university hospital with a high volume of people in the operating room. In this retrospective study, 1060 cats and dogs belonging to private owners were analysed for the occurrence of SSI over a period of almost 5 years, except during the COVID pandemic. Both the patient files were included, and the patient owners were contacted by questionnaire. The type of surgery, the use and type of AMP, as well as the occurrence, time, type and treatment of an SSI were documented. The overall SSI rate was 7.8 % (66/841). The use of an AMP did not lead to a significant reduction in risk in any of the surgeries analysed. Postoperative continuation of antibiotic prophylaxis showed no significant difference compared to perioperative prophylaxis alone. When interpreting the results, the retrospective nature of the study should be considered, as well as the fact that some of the results are based on a survey of patient owners.
本研究的目的是在一家手术室人员流量大的大型大学医院中，调查围手术期和术后抗菌预防（AMP）对择期使用抗生素手术中手术部位感染（SSI）的影响。在这项回顾性研究中，分析了近5年（COVID大流行期间除外）属于私人宠物主人的1060只猫和狗发生SSI的情况。纳入了患者档案，并通过问卷调查联系了患者主人。记录了手术类型、AMP的使用和类型，以及SSI的发生情况、时间、类型和治疗方法。总体SSI发生率为7.8%（66/841）。在所分析的任何手术中，使用AMP均未导致风险显著降低。与仅进行围手术期预防相比，术后继续进行抗生素预防无显著差异。在解释结果时，应考虑到研究的回顾性性质，以及部分结果基于对患者主人的调查这一事实。
