慢性血栓栓塞性肺动脉高压和肺动脉高压患者的运动训练：随机对照试验的系统评价和荟萃分析。
Exercise Training in Patients with Chronic Thromboembolic Pulmonary Hypertension and Pulmonary Arterial Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
机构信息
University of Michigan Medical School, 1301 Catherine Street, Ann Arbor, MI 48109, USA; Department of Internal Medicine, University of Michigan, 1500 East Medical Center Drive TC 311Q, Ann Arbor, MI 48109, USA.
Central Michigan University College of Medical School, 1200 South Franklin Street, Mount Pleasant, MI 48859, USA.
出版信息
Heart Fail Clin. 2025 Jan;21(1):137-148. doi: 10.1016/j.hfc.2024.05.003. Epub 2024 Oct 15.
Of the 5 randomized controlled trials (RCTs) included, chronic thromboembolic pulmonary hypertension (CTEPH) patients constituted 20% of the overall pulmonary hypertension (PH) patient population. We did not find any RCTs that evaluated the role of exercise training in patients with CTEPH. The results of this study indicate that exercise training may be effective at improving exercise capacity, as measured by 6-min walk distance, in patients with PH. Another notable finding from this analysis is the lack of adverse events associated with exercise training, suggesting that contrary to widespread perception, exercise training is safe in CTEPH and PAH patients.
在纳入的 5 项随机对照试验（RCT）中，慢性血栓栓塞性肺动脉高压（CTEPH）患者占总体肺动脉高压（PH）患者人群的 20%。我们没有发现任何评估运动训练在 CTEPH 患者中作用的 RCT。本研究结果表明，运动训练可能有效改善 PH 患者的运动能力，以 6 分钟步行距离衡量。该分析的另一个显著发现是运动训练与不良事件无关，这表明与普遍看法相反，运动训练在 CTEPH 和 PAH 患者中是安全的。
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