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人类红细胞的电泳迁移率。关于带电层模型的适用性。

Electrophoretic mobility of human erythrocytes. On the applicability of the charged layer model.

作者信息

Donath E, Voigt A

出版信息

Biophys J. 1986 Feb;49(2):493-9. doi: 10.1016/S0006-3495(86)83659-1.

DOI:10.1016/S0006-3495(86)83659-1
PMID:3955181
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1329489/
Abstract

The limitations of previous linear electrokinetic theories are discussed. A special model of the surface charge distribution, based on the minimum condition of the interfacial electrostatic free energy, is introduced. The model describes the electrophoretic mobility, taking into account the electroosmotic flow through the surface macromolecular layer and the surface conductivity. This nonlinear electrophoretic theory describes experimental data obtained with human erythrocytes. Numerical results for an uniformly distributed space charge are also presented.

摘要

讨论了先前线性电动理论的局限性。基于界面静电自由能的最小条件，引入了一种特殊的表面电荷分布模型。该模型考虑了通过表面大分子层的电渗流和表面电导率，描述了电泳迁移率。这种非线性电泳理论描述了用人红细胞获得的实验数据。还给出了均匀分布空间电荷的数值结果。

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本文引用的文献

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Calculation of the electrophoretic mobility of a particle bearing bound polyelectrolyte using the nonlinear poisson-boltzmann equation.使用非线性泊松-玻尔兹曼方程计算带有结合聚电解质的粒子的电泳迁移率。
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The action of lower aldehydes on the human erythrocyte.低级醛类对人体红细胞的作用。
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The surface charge of cells and some other small particles as indicated by electrophoresis. II. The interpretation of the electrophoretic charge.细胞及其他一些小颗粒的表面电荷（通过电泳显示）。II. 电泳电荷的解释。
Biochim Biophys Acta. 1961 Jul 8;50:457-62. doi: 10.1016/0006-3002(61)90004-x.
6
Electrostatic and structural properties of the surface of human erythrocytes. 3. Cell electrophoretical studies following addition of human serum albumin.人红细胞表面的静电和结构特性。3. 添加人血清白蛋白后的细胞电泳研究。
Acta Biol Med Ger. 1980;39(2-3):207-15.
7
Charge distribution within cell surface coats of single and interacting surfaces--a minimum free electrostatic energy approach. Conclusions for electrophoretic mobility measurements.
J Theor Biol. 1983 Apr 21;101(4):569-84. doi: 10.1016/0022-5193(83)90016-4.
8
Theory of the electrokinetic behavior of human erythrocytes.人类红细胞的电动行为理论
Biophys J. 1983 May;42(2):127-35. doi: 10.1016/S0006-3495(83)84378-1.
9
Bilayer membranes containing the ganglioside GM1: models for electrostatic potentials adjacent to biological membranes.含有神经节苷脂GM1的双层膜：生物膜相邻静电势的模型。
Biochemistry. 1984 Sep 25;23(20):4618-24. doi: 10.1021/bi00315a016.
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Electrophoresis of human leukocytes.
Arch Biochem Biophys. 1969 Dec;135(1):350-5. doi: 10.1016/0003-9861(69)90549-9.