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内镜辅助多支血管非体外循环冠状动脉旁路移植术:前100例手术经验

Endoscopic-Assisted Multivessel Off-Pump Coronary Artery Bypass Grafting: Experience of the First 100 Procedures.

作者信息

Görtzen De Qing, Sampon Fleur, Timmermans Naomi, Woorst Joost Ter, Akca Ferdi

机构信息

Department of Cardiothoracic Surgery, Catharina Hospital, Eindhoven, The Netherlands.

出版信息

J Chest Surg. 2025 Jan 5;58(1):21-30. doi: 10.5090/jcs.24.080. Epub 2024 Nov 18.

Abstract

BACKGROUND

This study presents an overview of our technique and the perioperative outcomes for the first 100 patients who underwent minimally invasive endoscopic-assisted off-pump multivessel bypass grafting (endoscopic coronary artery bypass [endo-CAB]) at the Catharina Hospital in Eindhoven.

METHODS

The first 100 patients undergoing multivessel endo-CAB from May 2022 to March 2024 were included in this retrospective, single-center, observational study (N=100). The study encompassed both elective and urgent surgical revascularization. In all cases, endoscopic-assisted harvesting of the internal mammary artery, radial artery, or saphenous vein was performed, followed by beating-heart anastomoses through a mini-thoracotomy.

RESULTS

A total of 226 distal anastomoses were performed, utilizing 102 left internal mammary arteries, 80 radial arteries, 30 right internal mammary arteries, and 14 saphenous veins. On average, each patient had 2.3 anastomoses. A Y graft configuration was employed in 78 patients, bilateral internal mammary artery inflow in 19 patients, and a proximal aortic graft in 3 patients. Four patients underwent concurrent arrhythmia surgery. Eleven patients received hybrid revascularization. There was 1 conversion to sternotomy (1%) and 3 instances where cardiopulmonary bypass was required (3%). The median operation time was 3.3 hours (interquartile range, 3.0-3.7 hours), and the median hospital stay was 4.0 days (interquartile range, 3-4 days). The in-hospital mortality rate was 1%.

CONCLUSION

Multivessel off-pump endo-CAB surgery can be safely performed with endoscopic-assisted conduit harvesting. Combining the benefits of a minimally invasive and anaortic approach may improve perioperative outcomes for patients requiring surgical revascularization. Further studies are necessary to establish the role of this technique in routine coronary surgery.

摘要

背景

本研究概述了我们的技术以及在埃因霍温的卡塔琳娜医院接受微创内镜辅助非体外循环多支血管搭桥术(内镜冠状动脉搭桥术[endo-CAB])的首批100例患者的围手术期结果。

方法

本回顾性单中心观察性研究纳入了2022年5月至2024年3月期间接受多支血管endo-CAB的首批100例患者(N = 100)。该研究涵盖了择期和急诊手术血运重建。在所有病例中,均采用内镜辅助获取胸廓内动脉、桡动脉或大隐静脉,随后通过小切口进行心脏不停跳吻合术。

结果

共进行了226次远端吻合,使用了102支左胸廓内动脉、80支桡动脉、30支右胸廓内动脉和14支大隐静脉。平均而言,每位患者有2.3次吻合。78例患者采用Y型移植构型,19例患者采用双侧胸廓内动脉流入,3例患者采用近端主动脉移植。4例患者同时进行了心律失常手术。11例患者接受了杂交血运重建。有1例转为胸骨切开术(1%),3例需要体外循环(3%)。中位手术时间为3.3小时(四分位间距,3.0 - 3.7小时),中位住院时间为4.0天(四分位间距,3 - 4天)。住院死亡率为1%。

结论

多支血管非体外循环endo-CAB手术可通过内镜辅助获取血管桥安全进行。结合微创和非体外循环方法的优点可能改善需要手术血运重建患者的围手术期结果。有必要进行进一步研究以确定该技术在常规冠状动脉手术中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afef/11738144/84d81fd9f5d0/jcs-58-1-21-f1.jpg

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