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偏头痛和紧张型头痛药物的全球可及性:国际头痛学会的调查。

Worldwide availability of medications for migraine and tension-type headache: A survey of the International Headache Society.

机构信息

Headache Group, Wolfson SPaRC, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.

出版信息

Cephalalgia. 2024 Nov;44(11):3331024241297688. doi: 10.1177/03331024241297688.

Abstract

BACKGROUND

In this study, we aimed to evaluate the differing global access to acute and preventive medications for migraine and tension-type headache.

METHODS

A custom-built questionnaire created by members of the International Headache Society Juniors Group was sent to International Headache Society members worldwide, including a list of acute and preventive treatments for migraine and tension-type headache. This list was based on evidence-based medicine guidelines. For each treatment, participants were asked about availability, type of reimbursement and variability of access within their country.

RESULTS

Eighty-four members completed the questionnaire providing data for 84 countries. The majority were neurologists (88%) and worked at an academic/university hospital (62%). Of participants, 36% were located in high-income economy countries and 13% were located in low-income economies. Common preventive treatments such as propranolol and topiramate were available in most countries (respectively in 99% and 92% of responding countries). Sumatriptan was available in most countries (95%), whereas other triptan availability was lower. Novel migraine treatments such as rimegepant and erenumab were only available in 14% and 46% of the assessed countries, respectively.

CONCLUSIONS

Availability of headache medications, ranging from simple analgesics to novel therapies migraine-specific drugs, varied greatly across the world. Actions are needed to improve effective drug availability in many countries to ensure an adequate management of people living with headache.

摘要

背景

在这项研究中,我们旨在评估全球在急性和预防性偏头痛和紧张型头痛药物方面的不同可及性。

方法

由国际头痛协会青少年组成员创建的定制问卷被发送给全球国际头痛协会成员,其中包括偏头痛和紧张型头痛的急性和预防性治疗清单。该清单基于循证医学指南。对于每种治疗方法,参与者被问及在其所在国家/地区的可用性、报销类型和获取途径的可变性。

结果

84 名成员完成了问卷,为 84 个国家提供了数据。他们大多数是神经病学家(88%),在学术/大学医院工作(62%)。参与者中有 36%位于高收入经济体国家,13%位于低收入经济体。常见的预防性治疗药物,如普萘洛尔和托吡酯,在大多数国家(分别在 99%和 92%的回答国家)都可以获得。大多数国家(95%)都可以获得舒马曲坦,但其他曲坦的可获得性较低。新型偏头痛治疗药物,如rimegepant 和 erenumab,仅分别在 14%和 46%的评估国家中可用。

结论

从简单的镇痛药到新型偏头痛特异性药物等头痛药物的可获得性在全球范围内差异很大。需要采取行动改善许多国家的有效药物供应,以确保患有头痛的人得到充分的管理。

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