Recent applications of pharmacometrics and systems pharmacology approaches to improve and optimize drug therapy for pregnant and lactating women.
作者信息
Jayachandran Priya, Knöchel Jane, Cicali Brian, Rowland Yeo Karen
机构信息
Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA.
Institute of Mathematics, University of Potsdam, Potsdam, Germany.
出版信息
CPT Pharmacometrics Syst Pharmacol. 2024 Nov;13(11):1815-1819. doi: 10.1002/psp4.13269. Epub 2024 Nov 18.
Abstract
摘要
相似文献
1
Recent applications of pharmacometrics and systems pharmacology approaches to improve and optimize drug therapy for pregnant and lactating women.药代动力学和系统药理学方法在改善和优化孕妇及哺乳期妇女药物治疗方面的最新应用。
CPT Pharmacometrics Syst Pharmacol. 2024 Nov;13(11):1815-1819. doi: 10.1002/psp4.13269. Epub 2024 Nov 18.
2
The convergence of pharmacometrics and quantitative systems pharmacology in pharmaceutical research and development.药物研发中药代动力学与定量系统药理学的融合。
Eur J Pharm Sci. 2023 Mar 1;182:106380. doi: 10.1016/j.ejps.2023.106380. Epub 2023 Jan 10.
3
Drug development research in pregnant and lactating women.妊娠期和哺乳期妇女的药物研发研究。
Am J Obstet Gynecol. 2021 Jul;225(1):33-42. doi: 10.1016/j.ajog.2021.04.227. Epub 2021 Apr 19.
4
Perspective on the State of Pharmacometrics and Systems Pharmacology Integration.药物代谢动力学与系统药理学整合的现状展望。
CPT Pharmacometrics Syst Pharmacol. 2018 Oct;7(10):617-620. doi: 10.1002/psp4.12313. Epub 2018 Aug 21.
5
CPT: Pharmacometrics and Systems Pharmacology.CPT：药物代谢动力学与系统药理学。
CPT Pharmacometrics Syst Pharmacol. 2012 Sep 26;1(9):e8. doi: 10.1038/psp.2012.8.
6
Advancing pharmacometrics and systems pharmacology.推进药物计量学和系统药理学。
Clin Pharmacol Ther. 2012 Nov;92(5):535-7. doi: 10.1038/clpt.2012.151.
7
Application of pharmacometrics and quantitative systems pharmacology to cancer therapy: The example of luminal a breast cancer.药物代谢动力学和定量系统药理学在癌症治疗中的应用：以 luminal A 型乳腺癌为例。
Pharmacol Res. 2017 Oct;124:20-33. doi: 10.1016/j.phrs.2017.07.015. Epub 2017 Jul 19.
8
Pharmacometrics: The Already-Present Future of Precision Pharmacology.药物代谢动力学：精准药理学的已然到来的未来。
Ther Innov Regul Sci. 2023 Jan;57(1):57-69. doi: 10.1007/s43441-022-00439-4. Epub 2022 Aug 18.
9
Clinical Pharmacology and Pharmacometrics to Better Understand Physiological Changes During Pregnancy and Neonatal Life.临床药理学与药物计量学，以更好地理解孕期和新生儿期的生理变化。
Handb Exp Pharmacol. 2020;261:325-337. doi: 10.1007/164_2019_210.
10
The status of pharmacometrics in pregnancy: highlights from the 3(rd) American conference on pharmacometrics.妊娠中的药物代谢动力学现状：第三届美国药物代谢动力学会议要点。
Br J Clin Pharmacol. 2012 Dec;74(6):932-9. doi: 10.1111/j.1365-2125.2012.04280.x.
本文引用的文献
1
Investigation of a fully mechanistic physiologically based pharmacokinetics model of absorption to support predictions of milk concentrations in breastfeeding women and the exposure of infants: A case study for albendazole.研究一种基于生理学的完全机制性吸收药代动力学模型，以支持预测哺乳期妇女乳汁中的药物浓度及婴儿的暴露量：以阿苯达唑为例的案例研究。
CPT Pharmacometrics Syst Pharmacol. 2024 Nov;13(11):1990-2001. doi: 10.1002/psp4.13260. Epub 2024 Nov 19.
2
Development of breakthrough bleeding model of combined-oral contraceptives utilizing model-based meta-analysis.利用基于模型的荟萃分析开发复方口服避孕药突破性出血模型。
CPT Pharmacometrics Syst Pharmacol. 2024 Nov;13(11):2016-2025. doi: 10.1002/psp4.13261. Epub 2024 Nov 17.
3
Physiologically based pharmacokinetic modeling of drug-drug interactions between ritonavir-boosted atazanavir and rifampicin in pregnancy.孕期利托那韦增强型阿扎那韦与利福平之间药物相互作用的基于生理的药代动力学建模
CPT Pharmacometrics Syst Pharmacol. 2024 Nov;13(11):1967-1977. doi: 10.1002/psp4.13268. Epub 2024 Nov 8.
4
Population pharmacokinetic modeling of paired plasma-breast milk lamivudine data for estimation of infant exposure in breastfeeding mother-infant pairs.对配对血浆-母乳拉米夫定数据进行群体药代动力学建模，以估计母乳喂养母婴对中婴儿的暴露情况。
CPT Pharmacometrics Syst Pharmacol. 2024 Nov;13(11):1978-1989. doi: 10.1002/psp4.13274. Epub 2024 Nov 7.
5
Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a recombinant human monoclonal antibody.通过基于靶标的药物处置模型和模拟告知妊娠剂量用于一种重组人源单克隆抗体。
CPT Pharmacometrics Syst Pharmacol. 2024 Nov;13(11):2002-2015. doi: 10.1002/psp4.13250. Epub 2024 Nov 4.
6
Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women.利用 PBPK 建模来补充临床数据，支持在孕妇和哺乳期妇女中安全有效地使用多替拉韦。
CPT Pharmacometrics Syst Pharmacol. 2024 Nov;13(11):1924-1938. doi: 10.1002/psp4.13251. Epub 2024 Oct 30.
7
Pharmacometrics in obstetrics and maternal-fetal medicine research: Bridging gaps in maternal and fetal pharmacology.妇产科与母胎医学研究中的药物计量学：弥合母胎药理学的差距
CPT Pharmacometrics Syst Pharmacol. 2024 Nov;13(11):1835-1840. doi: 10.1002/psp4.13267. Epub 2024 Oct 28.
8
Informing the risk assessment related to lactation and drug exposure: A physiologically based pharmacokinetic lactation model for pregabalin.在哺乳期和药物暴露相关的风险评估中：普瑞巴林的基于生理的药代动力学哺乳模型。
CPT Pharmacometrics Syst Pharmacol. 2024 Nov;13(11):1953-1966. doi: 10.1002/psp4.13266. Epub 2024 Oct 26.
9
Medicines in pregnancy: A clinical pharmacology extrapolation framework to address knowledge gaps.孕期用药：一个用于填补知识空白的临床药理学外推框架
CPT Pharmacometrics Syst Pharmacol. 2024 Nov;13(11):1830-1834. doi: 10.1002/psp4.13242. Epub 2024 Oct 14.
10
Physiologically based pharmacokinetic modeling of long-acting extended-release naltrexone in pregnant women with opioid use disorder.基于生理学的长效缓释纳曲酮在患有阿片类药物使用障碍的孕妇中的药代动力学模型。
CPT Pharmacometrics Syst Pharmacol. 2024 Nov;13(11):1939-1952. doi: 10.1002/psp4.13252. Epub 2024 Oct 9.
Zotero 插件