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一项基于医院的干预措施,旨在改善阿片类药物使用障碍患者获取丁丙诺啡的途径。

A Hospital-Based Intervention to Improve Access to Buprenorphine for Patients with Opioid Use Disorder.

作者信息

Fine Matthew, Hirt Wilner Leeza, Ormiston Cameron K, Wang Linda, Lee Trevor G, Herscher Michael

机构信息

Department of Medical Education, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Samuel Bronfman Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

出版信息

Subst Use Addctn J. 2025 Apr;46(2):377-383. doi: 10.1177/29767342241292416. Epub 2024 Nov 18.

Abstract

BACKGROUND

Opioid use disorder (OUD) is often under-addressed in hospitalized patients. In the absence of formal addiction consult services, volunteer physician-led models can increase access to inpatient OUD treatment. This paper describes a novel, volunteer physician-led interprofessional approach to identifying patients with OUD, initiating buprenorphine, and linking to office-based opioid treatment.

METHODS

The intervention took place from April 2018 to August 2020 at a large, urban, tertiary care center and teaching hospital in New York, NY that does not have an addiction consult service. Hospitalized patients with OUD were identified by provider-driven referrals or an automated daily patient list generated by a bioinformatics search algorithm. Eligible patients with OUD were started on buprenorphine during their hospitalization and linked to primary care-based buprenorphine treatment. Patients were followed longitudinally via chart review to assess follow-up clinic rates at >30 days, >60 days, >90 days, >6 months, >12 months, and >24 months after discharge.

RESULTS

Over a 2-year period, 178 patients were evaluated, 88 were eligible for inpatient buprenorphine, and 47 were started on buprenorphine while hospitalized. Sixty-seven patients were referred to a post-discharge visit at a primary care practice, 29 (43%) of whom attended an appointment at least 30 days after discharge. Of these, 22 (76%) returned at >60 days and 20 (69%) at 6 months. At the 1-year time point, 16 of a possible 17 patients (94%) and 15 of a possible 16 patients (94%) were still engaged in care at 2 years.

CONCLUSION

This intervention represents a proof of principle, adaptable model for identifying patients with OUD and engaging patients in primary care-based buprenorphine treatment. Limitations to consider include the sustainability of a volunteer-based initiative and that retention rates for 1 to 2 years post-discharge may be more indicative of the strengths of office-based opioid treatment itself as opposed to in-hospital engagement and the intervention.

摘要

背景

阿片类物质使用障碍(OUD)在住院患者中常常未得到充分关注。在缺乏正式成瘾咨询服务的情况下,由志愿医生主导的模式可以增加住院患者获得OUD治疗的机会。本文描述了一种由志愿医生主导的新型跨专业方法,用于识别患有OUD的患者、启动丁丙诺啡治疗,并与门诊阿片类物质治疗相衔接。

方法

干预措施于2018年4月至2020年8月在纽约市一家大型城市三级医疗中心和教学医院开展,该医院没有成瘾咨询服务。通过提供者驱动的转诊或生物信息学搜索算法生成的每日自动患者列表来识别患有OUD的住院患者。符合条件的OUD患者在住院期间开始使用丁丙诺啡,并与基于初级保健的丁丙诺啡治疗相衔接。通过病历审查对患者进行纵向随访,以评估出院后30天以上、60天以上、90天以上、6个月以上、12个月以上和24个月以上的随访门诊率。

结果

在2年期间,共评估了178例患者,其中88例符合住院使用丁丙诺啡的条件,47例在住院期间开始使用丁丙诺啡。67例患者被转诊至初级保健机构进行出院后随访,其中29例(43%)在出院后至少30天就诊。其中,22例(76%)在60天以上复诊,20例(69%)在6个月复诊。在1年时间点,可能的17例患者中有16例(94%),在2年时可能的16例患者中有15例(94%)仍在接受治疗。

结论

该干预措施代表了一种识别患有OUD的患者并使患者参与基于初级保健的丁丙诺啡治疗的原理验证、可适应模式。需要考虑的局限性包括基于志愿者的倡议的可持续性,以及出院后1至2年的留存率可能更能体现门诊阿片类物质治疗本身的优势,而非住院期间的参与情况和干预措施。

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