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嗜水气单胞菌坏死性蜂窝织炎的治疗与管理

Treatment and Management of Shewanella algae Necrotizing Cellulitis.

作者信息

Wang Alan, Hibdon Matthew, Desaraju Chakradhar, Liu-Young Gustine

机构信息

Osteopathic Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Clearwater, USA.

Family Medicine, Tampa General Hospital, Crystal River, USA.

出版信息

Cureus. 2024 Nov 14;16(11):e73680. doi: 10.7759/cureus.73680. eCollection 2024 Nov.

DOI:10.7759/cureus.73680
PMID:39552732
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11565497/
Abstract

is considered an emerging novel pathogenic cause of severe skin infections. The organism is a gram-negative motile bacillus commonly found in marine environments. While the more common causes of skin and soft tissue infections include , beta-hemolytic Streptococci, and/or have also been isolated in rare cases. Notably, this organism is more likely to cause infection in patients with open wounds and is commonly seen in patients with underlying diabetes and peripheral vascular disease. In this case, a 71-year-old male patient who developed severe necrotizing cellulitis infection of the left lower limb complicated by bacteremia. The patient was immediately started on empiric treatment with intravenous antibiotics until was identified; thereafter, the antibiotic treatment was adjusted accordingly. During the course of hospitalization, the patient required serial surgical debridement procedures to achieve source control. The purpose of the case report is to increase awareness among healthcare professionals on how infections are contracted, the clinical presentation and effects this microbe has on patients with chronic comorbidities, along with the antibiotic treatment, as no guidelines have been established thus far.

摘要

被认为是严重皮肤感染的一种新兴的新型致病原因。该生物体是一种革兰氏阴性运动杆菌,常见于海洋环境中。虽然皮肤和软组织感染的更常见原因包括 、β溶血性链球菌和/或 ,但在罕见病例中也分离出了 。值得注意的是,这种生物体更有可能在有开放性伤口的患者中引起感染,并且常见于患有基础糖尿病和外周血管疾病的患者中。在本病例中,一名71岁男性患者发生了左下肢严重坏死性蜂窝织炎感染并伴有菌血症。患者立即开始接受经验性静脉抗生素治疗,直到 被鉴定出来;此后,抗生素治疗相应调整。在住院期间,患者需要进行一系列外科清创手术以实现源头控制。该病例报告的目的是提高医疗保健专业人员对 感染如何感染、这种微生物对患有慢性合并症患者的临床表现和影响以及抗生素治疗的认识,因为迄今为止尚未建立相关指南。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df73/11565497/431f0a9bebbe/cureus-0016-00000073680-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df73/11565497/9db31e19bb62/cureus-0016-00000073680-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df73/11565497/c2d2a45bc424/cureus-0016-00000073680-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df73/11565497/dd7431ccf42e/cureus-0016-00000073680-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df73/11565497/431f0a9bebbe/cureus-0016-00000073680-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df73/11565497/9db31e19bb62/cureus-0016-00000073680-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df73/11565497/c2d2a45bc424/cureus-0016-00000073680-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df73/11565497/dd7431ccf42e/cureus-0016-00000073680-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df73/11565497/431f0a9bebbe/cureus-0016-00000073680-i04.jpg

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本文引用的文献

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Comparative Genomics Reveals Pathogenicity-Related Loci in .比较基因组学揭示了……中的致病相关基因座 。 (你提供的原文似乎不完整,“in”后面缺少具体内容 )
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