系统性硬化症患者的硬斑病样纹身反应：病例报告及文献复习
Morphea-like tattoo reaction in a patient with systemic sclerosis: Case report and review of the literature.
作者信息
Hobayan Catherine Grace P, Thai Jasmine, Korman Abraham M, Lin Judith
机构信息
Boonshoft School of Medicine, Wright State University, Dayton, OH, USA.
Division of Rheumatology and Immunology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
出版信息
J Scleroderma Relat Disord. 2024 Sep 10:23971983241272719. doi: 10.1177/23971983241272719.
BACKGROUND
Morphea-like tattoo reactions are rare phenomena, with few cases reported in the literature. We present a case of a morphea-like tattoo reaction and a literature review of such reactions for comparison.
CASE DESCRIPTION
A 38-year-old woman with known history of systemic sclerosis presented with abnormal healing and skin thickening over a red tattoo. Histopathological examination revealed sclerosing dermatitis, consistent with morphea-like tattoo reaction. Treatment included topical clobetasol and oral mycophenolate mofetil.
METHODS
A literature search of PubMed and EMBASE was performed in August 2023 for known morphea-like tattoo reactions. No time or language filters were applied.
RESULTS
A total of six articles were included. Case reports of morphea-like tattoo reactions in patients with no significant past medical history comprise five articles. One review article notes that red tattoo ink with and without cinnabar is associated with adverse skin reactions.
CONCLUSIONS
Morphea-like tattoo reactions can be triggered by ingredients of tattoo ink, possibly due to local hypersensitivity or the Koebner phenomenon. We encourage high clinical suspicion for morphea-like tattoo reactions when a patient with known history of connective tissue disease presents with skin changes around a tattoo.
背景
硬斑病样纹身反应是罕见现象，文献中报道的病例很少。我们报告一例硬斑病样纹身反应病例，并对这类反应进行文献综述以作比较。
病例描述
一名有系统性硬化症病史的38岁女性，红色纹身部位出现愈合异常和皮肤增厚。组织病理学检查显示硬化性皮炎，符合硬斑病样纹身反应。治疗包括外用氯倍他索和口服霉酚酸酯。
方法
2023年8月在PubMed和EMBASE上检索已知的硬斑病样纹身反应。未应用时间或语言筛选条件。
结果
共纳入6篇文章。5篇文章为无重大既往病史患者的硬斑病样纹身反应病例报告。一篇综述文章指出，含或不含朱砂的红色纹身颜料与皮肤不良反应有关。
结论
硬斑病样纹身反应可能由纹身颜料成分引发，可能是由于局部超敏反应或同形反应。当有结缔组织病病史的患者纹身周围出现皮肤改变时，我们鼓励对硬斑病样纹身反应保持高度临床怀疑。
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