Barqawi Abdelkarim M, Rostom Alaa, Suboh Duha, Hindi Inam, Odeh Razan, Abu Rass Hanood
Department of General Surgery, An-Najah National University Hospital, Nablus, PSE.
Department of Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus, PSE.
Cureus. 2024 Oct 17;16(10):e71673. doi: 10.7759/cureus.71673. eCollection 2024 Oct.
Melanoma is a malignant tumor that develops from the melanocyte-containing epithelial lining of mucosal membranes. This case report highlights a patient who presented with an asymptomatic decrease in hemoglobin (HGB), which necessitated an upper gastrointestinal (GI) endoscopy that identified a necrotic ulcerating lesion on the greater curvature of the stomach, which was confirmed to be a primary malignant gastric melanoma upon biopsy. The multidisciplinary team (MDT) subsequently recommended subtotal gastrectomy with D2 lymphadenectomy. After subsequent surgical intervention, the tumor was successfully removed with clear margins. A successful multidisciplinary approach led to favorable postoperative outcomes, highlighting the importance of timely diagnosis and management of rare presentations of melanoma.
黑色素瘤是一种起源于含黑素细胞的黏膜上皮的恶性肿瘤。本病例报告重点介绍了一名患者,该患者出现无症状血红蛋白(HGB)降低,因此需要进行上消化道(GI)内镜检查,检查发现胃大弯处有一个坏死性溃疡性病变,活检证实为原发性胃恶性黑色素瘤。多学科团队(MDT)随后建议行胃次全切除术加D2淋巴结清扫术。经过后续手术干预,肿瘤被成功切除,切缘清晰。成功的多学科方法带来了良好的术后结果,突出了及时诊断和处理黑色素瘤罕见表现的重要性。