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原发性胃黑色素瘤的成功管理:一例强调早期诊断和多学科方法重要性的病例报告

Successful Management of Primary Gastric Melanoma: A Case Report Emphasizing the Importance of Early Diagnosis and Multidisciplinary Approach.

作者信息

Barqawi Abdelkarim M, Rostom Alaa, Suboh Duha, Hindi Inam, Odeh Razan, Abu Rass Hanood

机构信息

Department of General Surgery, An-Najah National University Hospital, Nablus, PSE.

Department of Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus, PSE.

出版信息

Cureus. 2024 Oct 17;16(10):e71673. doi: 10.7759/cureus.71673. eCollection 2024 Oct.

Abstract

Melanoma is a malignant tumor that develops from the melanocyte-containing epithelial lining of mucosal membranes. This case report highlights a patient who presented with an asymptomatic decrease in hemoglobin (HGB), which necessitated an upper gastrointestinal (GI) endoscopy that identified a necrotic ulcerating lesion on the greater curvature of the stomach, which was confirmed to be a primary malignant gastric melanoma upon biopsy. The multidisciplinary team (MDT) subsequently recommended subtotal gastrectomy with D2 lymphadenectomy. After subsequent surgical intervention, the tumor was successfully removed with clear margins. A successful multidisciplinary approach led to favorable postoperative outcomes, highlighting the importance of timely diagnosis and management of rare presentations of melanoma.

摘要

黑色素瘤是一种起源于含黑素细胞的黏膜上皮的恶性肿瘤。本病例报告重点介绍了一名患者,该患者出现无症状血红蛋白(HGB)降低,因此需要进行上消化道(GI)内镜检查,检查发现胃大弯处有一个坏死性溃疡性病变,活检证实为原发性胃恶性黑色素瘤。多学科团队(MDT)随后建议行胃次全切除术加D2淋巴结清扫术。经过后续手术干预,肿瘤被成功切除,切缘清晰。成功的多学科方法带来了良好的术后结果,突出了及时诊断和处理黑色素瘤罕见表现的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3d5/11568405/9689fdb8071f/cureus-0016-00000071673-i01.jpg

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