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天然化合物与癌症:当前证据

Natural Compounds and Cancer: Current Evidences.

作者信息

Lianou Aikaterini D, Lianos Georgios D, Schizas Dimitrios, Machairas Nikolaos, Mitsis Michail, Alexiou George A

机构信息

Department of Surgery, University Hospital of Ioannina, Ioannina, Greece.

1nd Department of Propaedeutic Surgery, General Hospital Laiko, National and Kapodistrian University of Athens, Athens, Greece.

出版信息

Maedica (Bucur). 2024 Sep;19(3):621-628. doi: 10.26574/maedica.2024.19.3.621.

Abstract

Natural compounds are constantly gaining ground in the treatment of various chronic diseases and in cancer research. Recent efforts have been focusing on them due to their special features consisting of low toxicity and high bioavailability. These compounds have already demonstrated important antitumor activity against several cancers in vitro through several mechanisms, including cell viability reduction, suppression of cell proliferation, cell death induction and cell cycle arrest. Herewith, we reviewed natural compounds that can be potentially used for head and neck cancer, glioblastoma and gastrointestinal cancers.

摘要

天然化合物在各种慢性疾病的治疗和癌症研究中越来越受到关注。由于其具有低毒性和高生物利用度等特殊特性,最近人们的研究重点都集中在这些化合物上。这些化合物已经通过多种机制在体外对几种癌症表现出重要的抗肿瘤活性,包括降低细胞活力、抑制细胞增殖、诱导细胞死亡和使细胞周期停滞。在此,我们综述了可能用于头颈癌、胶质母细胞瘤和胃肠道癌的天然化合物。

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