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慢性咳嗽:肺部与心因性疾病之间的一种症状。一例误诊为支气管内错构瘤的病例。

Chronic Cough: a Symptom between Pulmonary and Psychogenic Disease. A Case of Misdiagnosed Endobronchial Hamartoma.

作者信息

Patsouras Alexandros, Patsouras Markos, Garmpis Nikolaos, Garmpi Anna, Diamantis Evangelos, Farmaki Paraskevi, Kyriakos Georgios, Savvanis Spyridon, Gravvanis Nikolaos, Damaskos Christos

机构信息

Second Department of Pulmonology, Sotiria General Hospital, Athens, Greece.

Department of Pathophysiology, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

出版信息

Maedica (Bucur). 2024 Sep;19(3):658-661. doi: 10.26574/maedica.2024.19.3.658.

Abstract

Endobronchial hamartoma is a benign mesenchymal tumor. It contains fat, cartilage and even bone tissue. It can be asymptomatic or cause respiratory symptoms such as cough and pneumonias. We report a case of a 68-year-old male who suffered from cough for the last four years. During this period of time, he was treated with different therapeutic approaches, including antibiotics, inhaled corticosteroids, pregabaline and bronchodilators, without clinical improvement. Allergic and gastrointestinal diseases were excluded. Pulmonary function tests were all normal. His symptoms had been attributed to anxiety disorder as psychogenic cough. However, a chest computed tomography (CT) was never conducted. Chest CT and bronchoscopy revealed an endobronchial hamartoma. Its endoscopical removal led to impressive remission of symptoms.

摘要

支气管内错构瘤是一种良性间叶组织肿瘤。它包含脂肪、软骨甚至骨组织。它可以无症状,也可引起咳嗽和肺炎等呼吸道症状。我们报告一例68岁男性,他在过去四年中一直咳嗽。在此期间,他接受了不同的治疗方法,包括抗生素、吸入性糖皮质激素、普瑞巴林和支气管扩张剂,但临床症状未改善。排除了过敏性和胃肠道疾病。肺功能测试均正常。他的症状曾被归因于焦虑症引起的心因性咳嗽。然而,从未进行过胸部计算机断层扫描(CT)。胸部CT和支气管镜检查发现了支气管内错构瘤。内镜下切除后症状明显缓解。

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本文引用的文献

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What's new in benign lung tumours?良性肺肿瘤有哪些新进展?
Histopathology. 2024 Jan;84(1):124-135. doi: 10.1111/his.15037. Epub 2023 Sep 10.
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Pulmonary Hamartomas: A Single-Center Analysis of 59 Cases.肺错构瘤:59例单中心分析
Eurasian J Med. 2022 Oct;54(3):270-273. doi: 10.5152/eurasianjmed.2022.21150.
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Endobronchial Hamartoma Presenting as Recurrent Pneumonia and Chronic Cough.
Cureus. 2021 Mar 5;13(3):e13717. doi: 10.7759/cureus.13717.
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Endobronchial hamartoma; a rare structural cause of chronic cough.支气管内错构瘤;慢性咳嗽的一种罕见结构病因。
Respir Med Case Rep. 2017 Aug 24;22:224-227. doi: 10.1016/j.rmcr.2017.08.019. eCollection 2017.
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Hamartomas from head to toe: an imaging overview.从头到脚的错构瘤:影像学概述
Br J Radiol. 2017 Mar;90(1071):20160607. doi: 10.1259/bjr.20160607. Epub 2016 Dec 12.
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Evidence-based Evaluation and Management of Chronic Cough.循证评估与管理慢性咳嗽。
Med Clin North Am. 2016 Sep;100(5):1033-45. doi: 10.1016/j.mcna.2016.04.008.

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