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纽芬兰与拉布拉多地区缺乏丁型肝炎(δ型肝炎)感染的证据。

Lack of evidence of hepatitis D (delta) infection in Newfoundland and Labrador.

作者信息

Ratnam S, Head C B, Butler R W

出版信息

CMAJ. 1986 Apr 15;134(8):905-7.

Abstract

Epidemiologic knowledge of hepatitis D virus (HDV) infection is limited. A seroepidemiologic study was undertaken to determine the prevalence of the infection in Newfoundland and Labrador. Between October 1983 and October 1985 over 200 people were recognized through routine serodiagnosis and screening as having hepatitis B seromarkers. A total of 223 serum samples from 186 of these people were tested for anti-HDV. The subjects were mainly asymptomatic carriers of hepatitis B surface antigen or patients with acute or chronic hepatitis B from the native Indian and Inuit and the non-native populations. None of the serum samples were positive for anti-HDV. The absence of anti-HDV in a substantial number of people in the province who are infected with hepatitis B virus is strong evidence that HDV infection is not prevalent in the local population, including native people.

摘要

丁型肝炎病毒(HDV)感染的流行病学知识有限。开展了一项血清流行病学研究,以确定纽芬兰和拉布拉多地区该感染的流行情况。1983年10月至1985年10月期间,通过常规血清学诊断和筛查,确认200多人有乙肝血清标志物。对其中186人的223份血清样本进行了抗HDV检测。研究对象主要是来自当地印第安人和因纽特人以及非本地人群的无症状乙肝表面抗原携带者或急慢性乙肝患者。所有血清样本的抗HDV检测均为阴性。该省大量感染乙肝病毒的人群中未检测到抗HDV,有力证明了HDV感染在当地人群(包括原住民)中并不流行。

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Delta infection among patients with chronic hepatitis B in the Stockholm region.
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Influence of delta infection on severity of hepatitis B.δ感染对乙型肝炎严重程度的影响。
Lancet. 1982 Oct 30;2(8305):945-7. doi: 10.1016/s0140-6736(82)90156-8.

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