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一名22岁男性,伴有头痛、面部麻木、复视和左腿麻木。

A 22-Year-Old Man With Headache, Facial Numbness, Diplopia and Left Leg Numbness.

作者信息

Moreira Daniel Gabay, Sanmartin Paul E

机构信息

Department of Neurology, University of Connecticut School of Medicine, Farmington, CT, USA.

Department of Neurology, Hartford Hospital, Hartford, CT, USA.

出版信息

Neurohospitalist. 2024 Aug 21:19418744241276711. doi: 10.1177/19418744241276711.

Abstract

We present a 22-year-old male with a subacute course of chin numbness, ophthalmoplegia, headache and left leg numbness in the setting of fever, chills and night sweats. Initial imaging investigations revealed cauda equina enhancement plus an infiltrative process at the basis of the skull associated with extensive bone marrow infiltration and lymphadenopathy elsewhere. We discuss the localization, differential diagnosis, and appropriate investigations for this unique clinical scenario. Important laboratory findings and treatment considerations are reviewed for this unusual final diagnosis.

摘要

我们报告一名22岁男性,在发热、寒战和盗汗的情况下,出现亚急性病程的下巴麻木、眼肌麻痹、头痛和左腿麻木。初始影像学检查显示马尾增强,以及颅底的浸润性病变,伴有广泛的骨髓浸润和其他部位的淋巴结病。我们讨论了这种独特临床情况的定位、鉴别诊断和适当的检查。针对这一不寻常的最终诊断,回顾了重要的实验室检查结果和治疗考虑因素。

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本文引用的文献

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Nat Rev Dis Primers. 2022 Dec 15;8(1):78. doi: 10.1038/s41572-022-00404-3.
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Blood. 2021 Feb 11;137(6):743-750. doi: 10.1182/blood.2019004099.
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