Hahn A W, Ruderman S A, Nance R M, Delaney Jac, Whitney B M, Eltonsy S, Haidar L, Drumright L N, Ma J, Mayer K H, O'Cleirigh C, Bamford L, Cachay E, Fox N T, Burkholder G, Cropsey K, Owens M A, Chander G, Crane H M, Fredericksen R J
University of Washington, Seattle, WA, USA.
University of Manitoba, Winnipeg, Manitoba, CA, Canada.
Drug Alcohol Depend Rep. 2024 Oct 28;13:100291. doi: 10.1016/j.dadr.2024.100291. eCollection 2024 Dec.
Cannabis use is highly prevalent and detrimental among people with HIV (PWH). Legislative changes in several states altered the legality and accessibility of cannabis. We examined pre-post legislative changes in current, daily, and severe use in PWH in clinical care.
PWH engaged in the Centers for AIDS Research Network of Integrated Clinical Systems (CNICS) cohort from 3 sites/states were asked about past 3-month cannabis use on a routine clinical assessment of health behavior before and after legalization. A fourth site in a state without legalization served as a comparator. We used linear regression to estimate changes in use prevalence from 1 year before to 1 year after legalization.
Among PWH (n=7885), from 1 year before to 1 year after legalization, cannabis use prevalence increased slightly in Boston, MA (32-38 %), Birmingham, AL (26-27 %), and San Diego, CA (25-29 %); and decreased in Seattle, WA (44-41 %). Contemporaneously, daily cannabis use increased modestly (less than 5 %) at all sites. Severe use (cannabis-specific ASSIST score ≥27) decreased or plateaued at all sites. No site showed significant change in prevalence trends of current, daily, or severe use 1 year before and after legalization in linear regression ( >0.05).
Few changes prevailed in cannabis use patterns around dates of legalization among PWH in care in the U.S. Relaxation of cannabis policy does not appear to result in an immediate increase in use among PWH.
大麻使用在艾滋病毒感染者（PWH）中非常普遍且有害。几个州的立法变化改变了大麻的合法性和可及性。我们研究了临床护理中PWH当前、每日和重度使用大麻情况在立法变化前后的情况。
参与综合临床系统艾滋病研究网络（CNICS）队列研究的来自3个地点/州的PWH在大麻合法化前后的健康行为常规临床评估中被问及过去3个月的大麻使用情况。一个未合法化州的第四个地点作为对照。我们使用线性回归来估计合法化前1年到合法化后1年使用流行率的变化。
在PWH（n = 7885）中，从合法化前1年到合法化后1年，马萨诸塞州波士顿（32 - 38%）、阿拉巴马州伯明翰（26 - 27%）和加利福尼亚州圣地亚哥（25 - 29%）的大麻使用流行率略有上升；华盛顿州西雅图（44 - 41%）的大麻使用流行率有所下降。同时，所有地点的每日大麻使用量适度增加（不到5%）。所有地点的重度使用（大麻特异性ASSIST评分≥27）下降或趋于平稳。在线性回归中，没有一个地点在合法化前后1年的当前、每日或重度使用流行率趋势显示出显著变化（P>0.05）。
在美国接受护理的PWH中，大麻合法化前后大麻使用模式几乎没有变化。大麻政策的放宽似乎并未导致PWH中大麻使用立即增加。
