阿霉素联合顺铂用于晚期甲状腺癌的II期评估：一项东南癌症研究组试验
Phase II evaluation of doxorubicin plus cisplatin in advanced thyroid cancer: a Southeastern Cancer Study Group Trial.
作者信息
Williams S D, Birch R, Einhorn L H
出版信息
Cancer Treat Rep. 1986 Mar;70(3):405-7.
PMID:3955552
Abstract
Twenty-two evaluable patients with all cell types of advanced thyroid cancer were treated with the combination of doxorubicin (60 mg/m2) plus cisplatin (60 mg/m2). There were two brief partial remissions (9.1%). There was considerable toxicity, with one drug-related death. Combination chemotherapy as given in this study was not effective for this patient population.
摘要
22例所有细胞类型的晚期甲状腺癌可评估患者接受了阿霉素（60mg/m²）加顺铂（60mg/m²）联合治疗。有2例短暂部分缓解（9.1%）。毒性反应相当大，有1例与药物相关的死亡。本研究中给予的联合化疗对该患者群体无效。
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