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心内膜心肌纤维化的术后评估

Postoperative evaluation of endomyocardial fibrosis.

作者信息

Balakrishnan K G, Venkitachalam C G, Pillai V R, Subramanian R, Valiathan M S

出版信息

Cardiology. 1986;73(2):73-84. doi: 10.1159/000173987.

Abstract

25 patients with angiographic features suggestive of endomyocardial fibrosis underwent endocardiectomy and atrioventricular valve replacement. There were 8 deaths. 17 survivors were reevaluated after a mean follow-up of 13.5 months. 8 had right ventricular endomyocardial fibrosis (RVEMF) 5 had left ventricular endomyocardial fibrosis (LVEMF) and 4 had biventricular disease (BVEMF). The survivors showed a significant improvement in their clinical features and functional status. There was a significant reduction in atrial size in X-ray. Hemodynamic data showed a significant fall in right heart filling pressure, right ventricular systolic pressure and pulmonary artery mean pressure, and a significant fall in left heart filling pressure in patients with left ventricular disease either alone or as a part of biventricular disease. In ventriculogram, while there was no change in right ventricular shape after endocardiectomy, left ventricular shape was restored to near normal. The significant improvement is mostly due to the correction of the regurgitant lesion and to some extent due to restoration of ventricular compliance.

摘要

25例具有心内膜心肌纤维化血管造影特征的患者接受了心内膜切除术和房室瓣膜置换术。其中8例死亡。17例幸存者在平均随访13.5个月后接受了重新评估。8例患有右心室心内膜心肌纤维化(RVEMF),5例患有左心室心内膜心肌纤维化(LVEMF),4例患有双心室疾病(BVEMF)。幸存者的临床特征和功能状态有显著改善。X线显示心房大小显著减小。血流动力学数据显示,单纯左心室疾病或作为双心室疾病一部分的患者,右心充盈压、右心室收缩压和肺动脉平均压显著下降,左心充盈压也显著下降。在心室造影中,心内膜切除术后右心室形状无变化,而左心室形状恢复至接近正常。显著改善主要归因于反流病变的纠正,在一定程度上也归因于心室顺应性的恢复。

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