联合习惯逆转疗法与接纳与承诺疗法治疗抽动秽语综合征的抽动症状：一项关于有效性和反应持续时间的初步研究
Combined Habit Reversal Therapy and Acceptance and Commitment Therapy for Treatment of Tics in Tourette Syndrome: A Pilot Study of Effectiveness and Response Duration.
作者信息
Eisenhauer Jennifer, Buckland Alison, Watson Stuart, Stell Rick
机构信息
Perron Institute for Neurological and Translational Sciences, UWA Medical School, University of Western Australia, Perth, Western Australia, Australia.
Watson Research and Statistics Consulting, Perth, Western Australia, Australia.
出版信息
Mov Disord Clin Pract. 2025 Jan;12(1):66-70. doi: 10.1002/mdc3.14260. Epub 2024 Nov 18.
BACKGROUND
Few studies have examined the effectiveness and duration of mindfulness-based therapies for tics in Tourette's syndrome. This study combined habit reversal therapy (HRT) with acceptance and commitment therapy (ACT).
OBJECTIVES
To evaluate the efficacy and response duration of HRT + ACT in reducing tic severity in adults with Tourette's Syndrome.
METHODS
Tic severity was assessed at baseline, post-intervention, and at 6- and 12-month follow-ups using the Yale Global Tic Severity Scale (YGTSS) and video assessments. The intervention included eight weekly 1-h sessions.
RESULTS
Mixed-effects regression showed significant reductions in tic severity post-treatment (b = -10.36, P = 0.002), maintained at 6 months (b = -8.19, P = 0.012) and 12 months (b = -8.82, P = 0.009). Video assessments confirmed these findings.
CONCLUSION
The HRT + ACT protocol effectively reduced tic severity, with benefits lasting 12 months. These results support further trials to compare HRT + ACT with HRT alone.
背景
很少有研究探讨基于正念的疗法对抽动秽语综合征患者抽动症状的有效性和持续时间。本研究将习惯逆转疗法（HRT）与接纳与承诺疗法（ACT）相结合。
目的
评估HRT + ACT对降低成人抽动秽语综合征患者抽动严重程度的疗效及反应持续时间。
方法
使用耶鲁综合抽动严重程度量表（YGTSS）和视频评估在基线、干预后以及6个月和12个月随访时评估抽动严重程度。干预包括每周一次，每次1小时，共8次治疗。
结果
混合效应回归显示治疗后抽动严重程度显著降低（b = -10.36，P = 0.002），在6个月（b = -8.19，P = 0.012）和12个月（b = -8.82，P = 0.009）时仍保持降低。视频评估证实了这些结果。
结论
HRT + ACT方案有效降低了抽动严重程度，且疗效持续12个月。这些结果支持进一步开展试验，以比较HRT + ACT与单纯HRT的效果。
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