Parizotto Flora Maziero, Cardoso Tânia Aparecida Marchiori de Oliveira, Brito Luiz Gustavo Oliveira, Juliato Cassia T
Department of Obstetrics and Gynecology, University of Campinas Faculty of Medical Sciences, Caixa Postal 6181, Campinas, SP, 13084-971, Brazil.
Department of Neurology, University of Campinas Faculty of Medical Sciences, Campinas, SP, Brazil.
Int Urogynecol J. 2025 Jan;36(1):147-156. doi: 10.1007/s00192-024-05974-2. Epub 2024 Nov 18.
Childhood enuresis may be associated with overactive bladder syndrome (OAB) in adulthood, which may contribute to sleep disorders. The objective was to compare the prevalence of childhood enuresis and sleep quality among women with and without OAB.
This mixed study included women with and without OAB, who completed an online questionnaire covering sociodemographic, urinary data, and five validated instruments in Portuguese: the Pittsburgh Sleep Quality Index (PSQI-BR), the Epworth Sleepiness Scale, the Berlin Questionnaire (QB-BR), the Modified Fatigue Impact Scale (MFIS-BR), and the Incontinence Questionnaire Overactive Bladder (ICIQ-OAB).
A total of 172 women were included, 86 in each group (OAB and non-OAB). The OAB group showed a higher prevalence of childhood enuresis (52.3% vs 25.6%, p < 0.001), poorer sleep quality on the PSQI-BR (9.6 ± 4.1 vs 5.7 ± 3.1, p < 0.001), more individuals classified as high risk of obstructive sleep apnea by the QB-BR (34.9% vs 15.1%, p < 0.001), higher impact on fatigue assessed by the MFIS-BR (39.3 ± 21.8 vs 17.8 ± 17.2, p < 0.001), and more daytime sleepiness according to the Epworth Sleepiness Scale (10.9 ± 6.1 vs 8.7 ± 4.8, p = 0.014). Women with OAB were associated with poor sleep quality, fatigue, obstructive sleep apnea, and daytime sleepiness. Childhood enuresis was associated with a 2.96 times higher chance of developing OAB (OR = 2.96; 95% CI: 1.41-6.19; p = 0.004).
Overactive bladder was associated with a higher prevalence of childhood enuresis, diminished sleep quality, elevated risk of obstructive sleep apnea, heightened fatigue, and increased daytime sleepiness among women. OAB increases the risk of sleep disorders and childhood enuresis increases the chances of developing OAB.
儿童期遗尿可能与成年期膀胱过度活动症（OAB）相关，这可能导致睡眠障碍。目的是比较患有和未患有OAB的女性中儿童期遗尿的患病率及睡眠质量。
这项混合研究纳入了患有和未患有OAB的女性，她们完成了一份在线问卷，内容涵盖社会人口统计学、尿液数据以及五份葡萄牙语的有效工具：匹兹堡睡眠质量指数（PSQI-BR）、爱泼华嗜睡量表、柏林问卷（QB-BR）、改良疲劳影响量表（MFIS-BR）以及膀胱过度活动症失禁问卷（ICIQ-OAB）。
共纳入172名女性，每组86名（OAB组和非OAB组）。OAB组儿童期遗尿的患病率更高（52.3%对25.6%，p<0.001），PSQI-BR睡眠质量更差（9.6±4.1对5.7±3.1，p<0.001），QB-BR将更多个体归类为阻塞性睡眠呼吸暂停高风险（34.9%对15.1%，p<0.001），MFIS-BR评估的疲劳影响更高（39.3±21.8对17.8±17.2，p<0.001），根据爱泼华嗜睡量表白天嗜睡情况更严重（10.9±6.1对8.7±4.8，p=0.014）。患有OAB的女性与睡眠质量差、疲劳、阻塞性睡眠呼吸暂停和白天嗜睡相关。儿童期遗尿与患OAB的几率高2.96倍相关（OR=2.96；95%CI：1.41-6.19；p=0.004）。
膀胱过度活动症与女性中儿童期遗尿的患病率更高、睡眠质量下降、阻塞性睡眠呼吸暂停风险升高、疲劳加剧以及白天嗜睡增加相关。OAB增加了睡眠障碍的风险，儿童期遗尿增加了患OAB的几率。
