Killer Alina, Köck Patrick, Klar Johanna, Lerch Stefan, Koenig Julian, Cavelti Marialuisa, Kindler Jochen, Kaess Michael
University Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.
Department of Psychosomatics and Psychotherapy, Clinic Barmelweid, Erlinsbach, Switzerland.
Psychopathology. 2025;58(3):152-159. doi: 10.1159/000541292. Epub 2024 Nov 18.
Differences in subjective stress perception and acute response of the hypothalamic-pituitary-adrenal axis have been reported in internet gaming disorder (IGD). The present study aimed to further investigate alterations in diurnal profiles of the endocrine stress response system in IGD compared to healthy controls (HCs).
The diurnal course of endocrine markers (salivary cortisol and α-amylase) was investigated in a clinical sample of n = 29 adolescents with IGD compared to n = 26 HC. Further, the effect of unrestricted gaming versus restricted gaming was examined within the IGD group.
No significant differences in salivary cortisol and α-amylase were observed comparing adolescents with IGD and HC. In addition, in the IGD group, there were no significant differences in salivary cortisol and α-amylase between conditions of unrestricted gaming versus restricted gaming. Compared to the HC group, the IGD group showed a significantly higher body mass index.
Our results indicate no alteration in diurnal profiles of the endocrine stress response in IGD.
已有报道称，互联网游戏障碍（IGD）患者在主观压力感知和下丘脑 - 垂体 - 肾上腺轴的急性反应方面存在差异。本研究旨在进一步调查与健康对照组（HCs）相比，IGD患者内分泌应激反应系统昼夜变化情况。
在一个临床样本中，对29名患有IGD的青少年和26名HCs的内分泌标志物（唾液皮质醇和α - 淀粉酶）的昼夜变化过程进行了研究。此外，还在IGD组内考察了无限制游戏与受限游戏的影响。
比较患有IGD的青少年和HCs时，未观察到唾液皮质醇和α - 淀粉酶有显著差异。此外，在IGD组中，无限制游戏与受限游戏条件下的唾液皮质醇和α - 淀粉酶也无显著差异。与HC组相比，IGD组的体重指数显著更高。
我们的结果表明，IGD患者内分泌应激反应的昼夜变化没有改变。
