State Key Laboratory of Green Pesticides, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals, Guizhou University, Guiyang 550025, China.
School of Pharmaceutical Sciences, Guizhou University, Guiyang 550025, China.
J Agric Food Chem. 2024 Nov 27;72(47):26057-26073. doi: 10.1021/acs.jafc.4c06538. Epub 2024 Nov 18.
Coumarin, a naturally occurring active ingredient with various biological activities in pesticides, is commonly found in plants belonging to the Rutaceae and Apiaceae families. Thanks to its unique structural properties and natural benefits, coumarin and its derivatives exhibit a wide range of physiological activities, including insecticidal, antifungal, antibacterial, herbicidal, and antiviral properties. These compounds have attracted considerable interest in the field of pesticide development, although there is a lack of comprehensive reviews on their use in pesticides. This Review aims to provide a detailed overview of the applications of coumarin and its derivatives in pesticides, covering biological activities, structure-activity relationship analyses, and mechanisms of action. It is hoped that this Review will offer new insights into the discovery and mechanisms of these compounds in pesticide development.
香豆素是一种天然存在的活性成分，具有多种生物活性，存在于芸香科和伞形科等植物中。由于其独特的结构特性和天然益处，香豆素及其衍生物表现出广泛的生理活性，包括杀虫、抗真菌、抗菌、除草和抗病毒活性。这些化合物在农药开发领域引起了相当大的兴趣，尽管它们在农药中的应用缺乏全面的综述。本综述旨在详细概述香豆素及其衍生物在农药中的应用，涵盖生物活性、构效关系分析和作用机制。希望本综述能为这些化合物在农药开发中的发现和作用机制提供新的见解。
