Chowdhury Raisa, Aldajani Ahmad, Almhanedi Hamad, Al Majid Dana, Tewfik Marc A, Himdi Lamiae
Faculty of Medicine and Health Science, McGill University, Montreal, QC, Canada.
Department of Otolaryngology Head & Neck Surgery, McGill University Health Centre, Montreal, QC, Canada.
Ann Otol Rhinol Laryngol. 2025 Mar;134(3):225-233. doi: 10.1177/00034894241300806. Epub 2024 Nov 19.
Paranasal sinus mucoceles, by virtue of extension into the orbit or cranial vault, can lead to significant ocular, nasal, or neural complications. There is limited comprehensive data on the presentation, management, and outcomes of cases with intraorbital or intracranial extension. A thorough analysis is essential to enhance clinical practices and improve patient outcomes.
This retrospective case series investigates the clinical presentations, radiological features, and surgical outcomes of 10 patients with paranasal sinus mucoceles exhibiting intraorbital or intracranial extensions.
Ten diagnosed cases of paranasal sinus mucoceles with intraorbital or intracranial extensions, as identified on CT or MRI imaging, were selected and retrieved from the electronic database of an academic-affiliated hospital from July 2013 to December 2023. Data were analyzed using descriptive statistics with IBM SPSS version 23.0 software.
The study revealed a mean patient age of 65 years, with females (60%) affected more than males (40%). The ethmoidal and frontal sinuses were predominantly involved, with varied clinical symptoms ranging from periorbital pain to visual disturbances. Radiologically, CT and MRI scans depicted extensive sinus involvement, often with intraorbital (50%), intracranial (20%), or combined (30%) extensions. Surgical interventions, primarily endoscopic sinus surgery, resulted in favorable outcomes, including symptom resolution, minimal complications, and no recurrence.
This case series emphasizes the importance of thorough preoperative evaluation, individualized surgical approaches, and vigilant postoperative care in managing mucoceles with orbital and cranial involvement. Further research with larger cohorts and extended follow-up periods is essential to refine treatment strategies and enhance patient outcomes for this complex pathology.
鼻窦黏液囊肿可因向眼眶或颅腔扩展而导致严重的眼部、鼻部或神经并发症。关于眼眶内或颅内扩展病例的表现、治疗和结果的综合数据有限。进行全面分析对于改进临床实践和改善患者预后至关重要。
本回顾性病例系列研究了10例表现为眼眶内或颅内扩展的鼻窦黏液囊肿患者的临床表现、影像学特征和手术结果。
从2013年7月至2023年12月一所附属医院的电子数据库中筛选并检索出10例经CT或MRI成像确诊为眼眶内或颅内扩展的鼻窦黏液囊肿病例。使用IBM SPSS 23.0软件进行描述性统计分析数据。
研究显示患者平均年龄为65岁，女性（60%）受累多于男性（40%）。筛窦和额窦受累为主，临床症状多样，从眶周疼痛到视力障碍不等。影像学上，CT和MRI扫描显示鼻窦广泛受累，常伴有眼眶内（50%）、颅内（20%）或两者合并（30%）扩展。手术干预主要是内镜鼻窦手术，取得了良好的效果，包括症状缓解、并发症极少且无复发。
本病例系列强调了在处理累及眼眶和颅腔的黏液囊肿时，术前全面评估、个体化手术方法和术后密切观察的重要性。进一步开展更大样本队列研究并延长随访时间对于完善治疗策略和改善这种复杂病理情况的患者预后至关重要。
