Takizawa Keita, Ozasa Kana, Shimada Akiko, Ogawa Toru, Iida Takashi, Oono Yuka, Sasaki Keiichi, Noma Noboru
Department of Oral Medicine, Nihon University School of Dentistry, 1-8-13, Kanda-Surugadai, Chiyoda-ku, Tokyo 101-8310, Japan.
Department of Oral Health Sciences, Faculty of Health Sciences, Osaka Dental University, Osaka, Japan.
Jpn Dent Sci Rev. 2024 Dec;60:250-257. doi: 10.1016/j.jdsr.2024.09.001. Epub 2024 Nov 5.
Phototherapy has emerged as a promising treatment for Bell's palsy, offering potential improvements in facial nerve function and overall well-being. In this study, we selected seven relevant studies involving 306 patients with subacute or acute Bell's palsy from PubMed, EMBASE, Web of Science, and Scopus before June 5, 2024. Low-level laser therapy (LLLT) efficacy for facial nerve paralysis was assessed in seven studies. Two studies lacked standard deviation data, precluding meta-analysis. Sunnybrook scores favored LLLT (mean difference [MD] = 17.42, 95 % confidence interval [CI]: 4.00-30.84, p = 0.011). However, Facial Disability Index results showed no significant difference (MD = 12.16, 95 % CI: -0.60 to 24.92, p = 0.061) between LLLT and control. LLLT, particularly with wavelengths of 830 or 850 nm administered over 6 weeks, may lead to beneficial outcomes. Combining LLLT with exercise therapy appears to be effective．LLLT demonstrates promise as a management option for Bell's palsy, potentially offering advantages over other treatments, particularly in patients with comorbidities, such as diabetes. Phototherapy devices currently used in Japan offer non-invasive treatment with minimal patient burden. The safety and therapeutic efficacy of these devices have been confirmed as a potential treatment for facial nerve paralysis.
光疗已成为一种有前景的贝尔面瘫治疗方法，有望改善面神经功能和整体健康状况。在本研究中，我们于2024年6月5日前从PubMed、EMBASE、科学网和Scopus中筛选了7项涉及306例亚急性或急性贝尔面瘫患者的相关研究。在7项研究中评估了低强度激光疗法（LLLT）对面神经麻痹的疗效。两项研究缺乏标准差数据，无法进行荟萃分析。桑尼布鲁克评分支持LLLT（平均差[MD]=17.42，95%置信区间[CI]：4.00 - 30.84，p = 0.011）。然而，面部残疾指数结果显示LLLT与对照组之间无显著差异（MD = 12.16，95%CI： - 0.60至24.92，p = 0.061）。LLLT，特别是波长为830或850nm且持续6周的治疗，可能会带来有益结果。将LLLT与运动疗法相结合似乎是有效的。LLLT作为贝尔面瘫的一种治疗选择显示出前景，可能比其他治疗方法更具优势，尤其是对于患有合并症（如糖尿病）的患者。日本目前使用的光疗设备提供非侵入性治疗，患者负担极小。这些设备的安全性和治疗效果已被确认为面神经麻痹的一种潜在治疗方法。
