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针灸治疗贝尔面瘫的疗效:随机对照试验的系统评价和荟萃分析

Efficacy of Acupuncture for Bell's Palsy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

作者信息

Li Pingping, Qiu Tangmeng, Qin Chao

机构信息

Department of Neurology, First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, China.

出版信息

PLoS One. 2015 May 14;10(5):e0121880. doi: 10.1371/journal.pone.0121880. eCollection 2015.

Abstract

Acupuncture has emerged as an alternative therapy for Bell's palsy in both adults and children. However, the use of acupuncture is controversial. We conducted a systematic review and meta-analysis to assess the efficacy of acupuncture for Bell's palsy. We searched PubMed, Embase, and the Cochrane Central Register of Controlled Trials, irrespective of any language restrictions. Randomized controlled trials comparing acupuncture with other therapies for Bell's palsy in adults or children were included. Fourteen randomized controlled trials involving 1541 individuals were included in this meta-analysis. Significant association was observed in acupuncture with a higher effective response rate for Bell's palsy (relative risk, 1.14; 95% confidence interval, 1.04-1.25; P = 0.005) but there was a heterogeneity among the studies (I2 = 87%). An assessment of the included studies revealed a high risk of bias in methodological quality. An evaluation of the incidence of complications was not available, owing to incomplete data. Acupuncture seems to be an effective therapy for Bell's palsy, but there was insufficient evidence to support the efficacy and safety of acupuncture. However, the results should be interpreted cautiously, because of the poor quality and heterogeneity of the included studies.

摘要

针灸已成为成人和儿童贝尔麻痹的一种替代疗法。然而,针灸的使用存在争议。我们进行了一项系统评价和荟萃分析,以评估针灸治疗贝尔麻痹的疗效。我们检索了PubMed、Embase和Cochrane对照试验中心注册库,不受任何语言限制。纳入了比较针灸与其他疗法治疗成人或儿童贝尔麻痹的随机对照试验。本荟萃分析纳入了14项涉及1541例个体的随机对照试验。观察到针灸与贝尔麻痹更高的有效反应率存在显著关联(相对危险度,1.14;95%置信区间,1.04 - 1.25;P = 0.005),但各研究之间存在异质性(I2 = 87%)。对纳入研究的评估显示,方法学质量存在高偏倚风险。由于数据不完整,无法评估并发症的发生率。针灸似乎是治疗贝尔麻痹的一种有效疗法,但没有足够的证据支持针灸的疗效和安全性。然而,由于纳入研究的质量差和异质性,对结果的解释应谨慎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f434/4431843/822697132063/pone.0121880.g001.jpg

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