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麦卢卡蜂蜜在乳突切除术后应用的一项干预性研究。

An Interventional Study of Application of Manuka Honey in Post Mastoidectomy Surgery.

作者信息

Jain Satish Kumar, Narang Shivam, Kacker Varun

机构信息

Otorhinolaryngology and Head & Neck Surgery, Jain ENT Hospital, Jaipur, Rajasthan India 23-24, Satya Vihar Colony, Pankaj Singhavi Marg, Nr. Vidhan Sabha,Lal Kothi, 302015.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Dec;76(6):5272-5276. doi: 10.1007/s12070-024-04962-8. Epub 2024 Aug 7.

Abstract

The aim of present study was to observe the effect of topical application of manuka honey in healing in the healing of postoperative mastoid cavity. A total of 100 patients diagnosed with chronic suppurative otitis media with cholesteatoma underwent canal wall down mastoidectomy, Manuka honey-soaked roller gauze pack was placed on Day 10 and was removed on day 17 and manuka honey was applied on day 17. Cavity was assessed on day 47 and day 90 on follow-up. Otoendoscopy was done on every visit to assess mastoid cavity. The primary outcome measure was the creation of a dry cavity as measured by a semi-quantitative scale as described by Merchant et al. Then Mastoid Cavity Healing Score was calculated on every visit and scoring was done at the end. On intragroup comparison it appeared that both the treatment methods exhibited improvised merchant grade score with the course of time (-value = < 0.001). At 47th day and 90th day, the healing score in Group A was significantly higher than in Group B [-value = < 0.001 and 0.001] respectively. We recommend Manuka honey as an adjunct to achieve a safe, dry ear in view of faster epithelization after mastoidectomy.

摘要

本研究的目的是观察局部应用麦卢卡蜂蜜对术后乳突腔愈合的影响。共有100例被诊断为慢性化脓性中耳炎伴胆脂瘤的患者接受了开放式乳突根治术,在第10天放置麦卢卡蜂蜜浸泡的纱条并于第17天取出,在第17天应用麦卢卡蜂蜜。在随访的第47天和第90天对乳突腔进行评估。每次就诊时均进行耳内镜检查以评估乳突腔。主要结局指标是按照Merchant等人描述的半定量量表来衡量形成干耳。然后在每次就诊时计算乳突腔愈合评分,并在最后进行评分。组内比较显示,随着时间的推移,两种治疗方法的Merchant分级评分均有所改善(P值<0.001)。在第47天和第90天,A组的愈合评分分别显著高于B组[P值分别<0.001和0.001]。鉴于乳突切除术后上皮化更快,我们推荐使用麦卢卡蜂蜜作为辅助手段以实现安全的干耳。

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