Gowthame K, Prabakaran S, Navin R B Namasivaya, Rajasekaran S, Muthukumar R, Balaji D, Kumar B Sarath, Adithya V
Department Of Otorhinolaryngology, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam, Tamil Nadu 603103 India.
Indian J Otolaryngol Head Neck Surg. 2024 Dec;76(6):5256-5262. doi: 10.1007/s12070-024-04957-5. Epub 2024 Aug 7.
Chronic suppurative otitis media is a prolonged and chronic condition. It is a prevalent bacterial infection in the field of otolaryngology that has substantial consequences. Prior to surgical intervention, it is crucial to implement medical treatment to make the ears dry in cases of chronic suppurative otitis media. The goal is to determine the most suitable agent for aural toileting in individuals with chronic suppurative otitis media by evaluating the outcomes of irrigation of acetic acid and gentian violet and determining the most suitable treatment. A randomized controlled study was done on 100 patients in a tertiary care center with a tubotympanic type of CSOM in the active phase. Patients were divided into 2 groups and toileting and irrigation were done with acetic acid in one group and with gentian violet in the other for 3 weeks. The comparison of treatment outcomes between the groups revealed a statistically significant difference, with acetic acid demonstrating superior treatment results compared to gentian violet. This was further confirmed by a statistically significant difference between the two groups in otologic scores at different time points, as a result of a considerably greater fall in scores in the acetic acid group. Regular antiseptic auditory cleaning and irrigation can help manage chronic suppurative otitis media. The process of healing is facilitated by modifying the pH of the ear canal, reducing inflammation, destroying biofilms, and removing exudates. Acetic acid appears to be more effective than gentian violet in treating the condition. Therefore, acetic acid alone or in conjunction with antibiotic ear drops, can be used for the treatment of chronic suppurative otitis media.
慢性化脓性中耳炎是一种迁延不愈的慢性病症。它是耳鼻喉科领域常见的细菌感染，会产生严重后果。在进行手术干预之前，对于慢性化脓性中耳炎患者，实施药物治疗以使耳朵干燥至关重要。目的是通过评估醋酸和龙胆紫冲洗的效果并确定最合适的治疗方法，来确定慢性化脓性中耳炎患者最适合的耳道清理剂。在一家三级护理中心对100例处于活动期的鼓室黏膜型慢性化脓性中耳炎患者进行了一项随机对照研究。患者被分为两组，一组用醋酸进行耳道清理和冲洗，另一组用龙胆紫进行耳道清理和冲洗，为期3周。两组治疗结果的比较显示出统计学上的显著差异，与龙胆紫相比，醋酸显示出更好的治疗效果。两组在不同时间点的耳科评分存在统计学上的显著差异，进一步证实了这一点，因为醋酸组的评分下降幅度要大得多。定期进行抗菌性耳道清洁和冲洗有助于控制慢性化脓性中耳炎。通过改变耳道pH值、减轻炎症、破坏生物膜和清除渗出物，促进愈合过程。在治疗这种病症方面，醋酸似乎比龙胆紫更有效。因此，单独使用醋酸或与抗生素耳滴剂联合使用，可用于治疗慢性化脓性中耳炎。
