Rajbhar Krishan, Tuli Isha Preet, Lal Priti, Sai Ravi Sasank
Department of ENT, ORL International Hospital, New Delhi, India.
Department of ENT, VMMC & Safdarjung Hospital, New Delhi, India.
Indian J Otolaryngol Head Neck Surg. 2024 Dec;76(6):5364-5368. doi: 10.1007/s12070-024-04978-0. Epub 2024 Aug 24.
Gustation is affected in patients of Chronic rhinosinusitis (CRS) depending on severity of diseases. This study aimed to find the prevalence of gustatory dysfunction in patients with CRS. This case-control study included 61 patients with CRS and 61 healthy controls. Patients were subjected to non-contrast CT scan of the paranasal sinuses. Disease severity was assessed using the Lund Mackay Scoring. Gustatory assessment was done as per scoring of Mueller et al. Taste score of 9 or more was considered normal. The outcome measures were gustatory dysfunction and association with presence of polyps and CRS severity. P-value < 0.05 was considered statistically significant. Compared to controls, cases had significantly lower total taste scores (12 vs. 15, < 0.001). Gustatory dysfunction was seen among 13 (21.3%) patients. It was significantly more among those with polyps than without [8(53.3%) vs. 5(10.9%), < 0.05]. There was a significant negative correlation between the gustatory dysfunction scores and the severity of CRS (=-0.664, < 0.001). In conclusion, we report a prevalence of gustatory dysfunction in 21.3% cases of CRS which was negatively affected by the presence of nasal polyps and CRS severity.
The online version contains supplementary material available at 10.1007/s12070-024-04978-0.
慢性鼻-鼻窦炎(CRS)患者的味觉会因疾病严重程度而受到影响。本研究旨在找出CRS患者中味觉功能障碍的患病率。这项病例对照研究纳入了61例CRS患者和61名健康对照者。对患者进行了鼻窦非增强CT扫描。使用Lund-Mackay评分评估疾病严重程度。根据Mueller等人的评分进行味觉评估。味觉评分为9分或更高被认为是正常的。观察指标为味觉功能障碍以及与息肉存在和CRS严重程度的关联。P值<0.05被认为具有统计学意义。与对照组相比,病例组的总味觉评分显著更低(12分对15分,<0.001)。13例(21.3%)患者存在味觉功能障碍。有息肉的患者中味觉功能障碍的比例显著高于无息肉患者[8例(53.3%)对5例(10.9%),<0.05]。味觉功能障碍评分与CRS严重程度之间存在显著负相关(=-0.664,<0.001)。总之,我们报告CRS患者中味觉功能障碍的患病率为21.3%,其受到鼻息肉的存在和CRS严重程度的负面影响。
在线版本包含可在10.1007/s12070-024-04978-0获取的补充材料。