Kim James H, Choi Janet, Jang Sophie S, Wrobel Bozena B, Ference Elisabeth H
Caruso Department of Otolaryngology-Head and Neck Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Royal College of Surgeons in Ireland, Dublin, Republic of Ireland.
OTO Open. 2021 Feb 2;5(1):2473974X20986756. doi: 10.1177/2473974X20986756. eCollection 2021 Jan-Mar.
To estimate the prevalence of objectively confirmed olfactory and gustatory dysfunction in US adults reporting chronic rhinosinusitis (CRS) symptoms in a nationally representative database.
Cross-sectional epidemiologic analysis.
Data were analyzed from the smell and taste component of the 2013-2014 NHANES data set (National Health and Nutrition Examination Survey).
Individuals reporting the presence of ≥2 cardinal CRS symptoms (nasal blockage, sinus pain, discolored mucus, and dysosmia) were identified as patients with a potential diagnosis of CRS. Associations were examined between the presence of CRS symptoms and both self-reported and objectively measured smell and taste.
One-third (33%) of adults who have ≥2 CRS symptoms report subjective olfactory impairment, though only 18% of these adults have quantifiable olfactory dysfunction on objective testing. Of these adults, 27% report subjective taste impairment, but just 17% have quantifiable gustatory dysfunction on objective testing. The presence of ≥2 CRS symptoms was not significantly associated with objective olfactory or gustatory dysfunction, although the individual symptoms of subjective dysosmia and discolored mucus were associated with objectively confirmed olfactory dysfunction.
The prevalence of objective olfactory and gustatory dysfunction was higher among adults reporting the presence of ≥2 CRS symptoms, but the differences were not statistically significant. Specific sinonasal symptoms, including discolored mucus and subjective smell dysfunction, were significantly associated with objective smell impairment.
在一个具有全国代表性的数据库中，估计报告有慢性鼻窦炎（CRS）症状的美国成年人中经客观证实的嗅觉和味觉功能障碍的患病率。
横断面流行病学分析。
对2013 - 2014年美国国家健康与营养检查调查（NHANES）数据集的嗅觉和味觉部分数据进行分析。
将报告有≥2种主要CRS症状（鼻塞、鼻窦疼痛、鼻涕变色和嗅觉障碍）的个体确定为可能诊断为CRS的患者。研究CRS症状的存在与自我报告及客观测量的嗅觉和味觉之间的关联。
有≥2种CRS症状的成年人中，三分之一（33%）报告有主观嗅觉障碍，但这些成年人中只有18%在客观测试中有可量化的嗅觉功能障碍。在这些成年人中，27%报告有主观味觉障碍，但客观测试中只有17%有可量化的味觉功能障碍。≥2种CRS症状的存在与客观嗅觉或味觉功能障碍无显著关联，不过主观嗅觉障碍和鼻涕变色等个体症状与经客观证实的嗅觉功能障碍有关。
报告有≥2种CRS症状的成年人中，客观嗅觉和味觉功能障碍的患病率较高，但差异无统计学意义。特定的鼻窦症状，包括鼻涕变色和主观嗅觉功能障碍，与客观嗅觉损害显著相关。
