Cohen J D, Viljoen M, Clifford D, De Oliveria A A, Veriava Y, Milne F J
Clin Nephrol. 1986 Jan;25(1):42-7.
Plasma vitamin E levels and the ascorbate cyanide test were assessed in 15 chronic hemodialysis (HD) patients (group A) exposed to persistently elevated chloramine levels in the dialysis water. The vitamin E levels in these patients, who had evidence of oxidant induced hemolytic anemia, were compared to 15 chronic HD patients exposed to low chloramine levels (group B) and 17 controls (group C). Vitamin E levels were found to be significantly lower in group A than in either groups B or C (p less than 0.001). Within group A, levels were lower in those patients who had a positive ascorbate cyanide test (p less than 0.05). Upon removal of chloramines from the dialysis water, vitamin E levels in group A were no longer significantly different from those found in groups B or C.
对15名长期暴露于透析水中氯胺水平持续升高的慢性血液透析（HD）患者（A组）的血浆维生素E水平和抗坏血酸氰化物试验进行了评估。将这些有氧化剂诱导的溶血性贫血证据的患者的维生素E水平与15名暴露于低氯胺水平的慢性HD患者（B组）和17名对照者（C组）进行了比较。发现A组的维生素E水平显著低于B组或C组（p<0.001）。在A组中，抗坏血酸氰化物试验呈阳性的患者维生素E水平较低（p<0.05）。从透析水中去除氯胺后，A组的维生素E水平与B组或C组不再有显著差异。
