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内镜下黏膜下切除术联合鼻甲成形术及部分下鼻甲切除术治疗下鼻甲肥大:一项随机临床试验

Endoscopic Submucosal Resection Turbinoplasty and Partial Inferior Turbinectomy for Management of Inferior Turbinate Hypertrophy: A Randomized Clinical Trial.

作者信息

Easa Sabry Habshey, Farghaly Talaat Mahrous, Elswaby El Sayed Said, Selim Ahmed

机构信息

Lecturer of Otorhinolaryngology, Faculty of Medicine, Al-Azhar University, Assiut, MD Egypt.

Faculty of Medicine, Al-Azhar University, Assiut, MD Egypt.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Dec;76(6):5080-5090. doi: 10.1007/s12070-024-04926-y. Epub 2024 Aug 8.

DOI:10.1007/s12070-024-04926-y
PMID:39559133
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11569076/
Abstract

OBJECTIVES

This study aims to compare outcomes of endoscopic submucosal resection Turbinoplasty and partial inferior turbinectomy in the treatment of Chronic inferior turbinate hypertrophy.

METHODS

A randomized prospective comparative study was conducted on 40 patients who complained of a minimum 3-month duration of nasal obstruction combined with clinical findings of moderate to severe inferior turbinate hypertrophy. Patients were divided into two groups: Group A (Endoscopic submucosal resection Turbinoplasty), and Group B (partial inferior turbinectomy) Which included 20 patients in each group. The outcomes of both techniques were analyzed and compared.

RESULTS

A total of 40 patients were randomized with 20 patients assigned to each group. Within each group, there were 12 (60%) females and 8 (40%) males. The median age in Group A was 22.7 (IQR, 7.50), and 26.5 (IQR, 15.5) in Group B. There were statistically significant differences between the two groups regarding nasal obstruction, nasal discharge, and crustations favoring Group A ( < 0.001, 0.003, 0.013 respectively). Additionally, there was a statistically significant increase in anterior nasal space postoperatively in Group A over Group B ( < 0.001) while a statistically significant increase in posterior nasal space was detected in Group B over Group A ( < 0.001). Also, there was a statistically significant reduction in turbinate size anteriorly and posteriorly in Group B over Group A ( < 0.001).

CONCLUSION

submucosal resection Turbinoplasty is a safe and reliable technique of high efficacy and minimal complications that allows precise excision of hypertrophied stromal tissue in a submucosal plane which protects the physiological function of overlying respiratory precious mucosa and has minimal complications.

TRIAL REGISTRATION

the trial was retrospectively registered at Clinical Trail.Gov identifier: NCT06310083.

摘要

目的

本研究旨在比较内镜下黏膜下鼻甲成形术和部分下鼻甲切除术治疗慢性下鼻甲肥大的效果。

方法

对40例主诉鼻塞至少3个月且伴有中重度下鼻甲肥大临床表现的患者进行了一项随机前瞻性对照研究。患者分为两组:A组(内镜下黏膜下鼻甲成形术)和B组(部分下鼻甲切除术),每组各20例。对两种技术的效果进行了分析和比较。

结果

共40例患者被随机分组,每组20例。每组中,女性12例(60%),男性8例(40%)。A组的中位年龄为22.7岁(四分位间距,7.50),B组为26.5岁(四分位间距,15.5)。两组在鼻塞、鼻分泌物和结痂方面存在统计学显著差异,A组更具优势(分别为<0.001、0.003、0.013)。此外,A组术后鼻前间隙较B组有统计学显著增加(<0.001),而B组术后鼻后间隙较A组有统计学显著增加(<0.001)。同时,B组下鼻甲前后径较A组有统计学显著减小(<0.001)。

结论

黏膜下鼻甲成形术是一种安全可靠、疗效高且并发症少的技术,能够在黏膜下平面精确切除肥厚的基质组织,保护覆盖的呼吸珍贵黏膜的生理功能,并发症极少。

试验注册

该试验在Clinical Trail.Gov上进行了回顾性注册,标识符为:NCT06310083。

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Surgical Interventions for Inferior Turbinate Hypertrophy: A Comprehensive Review of Current Techniques and Technologies.下鼻甲肥大的手术干预:当前技术和方法的全面综述。
Int J Environ Res Public Health. 2021 Mar 26;18(7):3441. doi: 10.3390/ijerph18073441.
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