Maharjan Narendra, Sharma Deepak, Pradhan Sumita, Kandel Bishnu P, Lakhey Paleswan Joshi, Bhandari Ramesh S
Department of Surgical Gastroenterology, Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, NPL.
Cureus. 2024 Oct 19;16(10):e71858. doi: 10.7759/cureus.71858. eCollection 2024 Oct.
Background Liver transplantation is the standard treatment for end-stage liver disease. Living donor liver transplantation is more commonly performed in Asian countries as compared to the Western due to the lack of organ donation. Donor safety is the key to sustaining a liver transplant program. Thus, we aimed to evaluate the overall safety of living donors and health-related quality of life using the 12-item Short Form Health Survey (SF-12) questionnaire at our institution. Methodology We analyzed the medical records of patients who underwent donor hepatectomy at Tribhuvan University Teaching Hospital, Kathmandu, from May 31, 2019, to April 18, 2023. Demography, postoperative complications, and quality of life were analyzed. Results The mean age of the 10 live liver donors was 27.9 years. Half of them were male. One of them had a post-hepatectomy bile leak and others did not have any post-operative complications. They have good physical and mental health status after liver donation as indicated by the average physical component summary and mental component summary scores of more than 50. Conclusion The case series highlights the safety and favorable outcomes of liver donors at a low-volume liver transplant center, where stringent preoperative assessments and careful surgical techniques were employed.
背景 肝移植是终末期肝病的标准治疗方法。由于器官捐赠匮乏，与西方国家相比，活体肝移植在亚洲国家更为常见。供体安全是维持肝移植项目的关键。因此，我们旨在使用12项简短健康调查问卷（SF-12）评估我院活体供体的总体安全性和与健康相关的生活质量。方法 我们分析了2019年5月31日至2023年4月18日在加德满都特里布万大学教学医院接受供体肝切除术患者的病历。分析了人口统计学、术后并发症和生活质量。结果 10名活体肝供体的平均年龄为27.9岁。其中一半为男性。其中1例发生肝切除术后胆漏，其他患者无任何术后并发症。肝脏捐赠后，他们的身心健康状况良好，平均身体成分总结和心理成分总结得分均超过50分。结论 该病例系列突出了一个低容量肝移植中心肝供体的安全性和良好结局，该中心采用了严格的术前评估和细致的手术技术。
