Lindberg H
Clin Orthop Relat Res. 1986 Feb(203):273-5.
The prevalence of primary coxarthrosis was investigated in 289 siblings of 184 patients treated by total hip replacement. Age and sex-matched persons from the city files of Malmö, Sweden, were selected as controls. The prevalence of presenting symptoms (initiating a hip roentgen examination) of primary coxarthrosis in the siblings was 8%, compared to 3.8% in the controls (p less than 0.05). The type and localization of primary coxarthrosis was evenly distributed between the two groups. Conversely, the prevalence of gonarthrosis did not differ between the two groups. The prevalence of primary coxarthrosis in the siblings suggests the influence of a hereditary factor in the etiology of primary coxarthrosis.
对184例接受全髋关节置换术患者的289名兄弟姐妹进行了原发性髋关节炎患病率的调查。选取瑞典马尔默市档案中年龄和性别匹配的人员作为对照。兄弟姐妹中出现原发性髋关节炎症状(引发髋关节X线检查)的患病率为8%,而对照组为3.8%(p<0.05)。原发性髋关节炎的类型和部位在两组之间分布均匀。相反,两组间膝关节炎的患病率没有差异。兄弟姐妹中原发性髋关节炎的患病率表明遗传因素在原发性髋关节炎病因中具有影响。