Department of Neurosurgery, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia.
CNS Oncol. 2024 Dec 31;13(1):2415279. doi: 10.1080/20450907.2024.2415279. Epub 2024 Nov 19.
Epidermoid cysts are uncommon accounting for less than 1% of all intracranial tumors. Among them, giant intradiploic epidermoid cysts of the posterior fossa i.e. those exceeding 5 cm are an even rarer entity. Here we report on the complete resection of a 7 cm posterior fossa epidermoid cyst involving the occipital bone in a 32-year-old female presenting with an acute on chronic exacerbation of headaches and vertigo. Complete resection including the cyst wall is crucial in preventing recurrence and malignant transformation. We add to limited existing data by reporting on the first systematic review to date assessing 25 cases of giant epidermoid cysts of the posterior fossa to discuss presentation, clinical and radiographic features and definitive management strategies.
表皮样囊肿少见,占颅内肿瘤的比例不足 1%。其中,后颅窝巨大硬膜内表皮样囊肿(即直径超过 5cm 的囊肿)更为罕见。我们报告了一例 32 岁女性患者,其存在慢性头痛和眩晕的急性加重,接受了 7cm 后颅窝表皮样囊肿的完全切除术,该囊肿累及枕骨。包括囊肿壁在内的完全切除对于预防复发和恶变至关重要。我们通过报告迄今为止首次评估 25 例后颅窝巨大表皮样囊肿的系统评价,添加了有限的现有数据,以讨论其表现、临床和影像学特征以及明确的治疗策略。