• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

大鼠胃和十二指肠黏液糖蛋白的比较研究

Comparative study on mucus glycoproteins in rat stomach and duodenum.

作者信息

Ohara S, Ishihara K, Hotta K

出版信息

Comp Biochem Physiol B. 1986;83(2):273-5. doi: 10.1016/0305-0491(86)90365-2.

DOI:10.1016/0305-0491(86)90365-2
PMID:3956151
Abstract

The density of mucus glycoprotein compared to that of the corpus, antrum and duodenum was; 1.52, 1.49 and 1.57 g/ml respectively. Carbohydrate composition of gastrointestinal mucus glycoprotein consisted of N-acetylgalactosamine, N-acetylglucosamine, galactose, fucose and sialic acid. Ratios of carbohydrate composition among corpus, antral and duodenal mucus glycoproteins differed. The average length of an oligosaccharide was found to be about 12-13, 14 and 10 sugars in the corpus, antrum and duodenum, respectively. In the corpus, the amino acid content was found to have the following quantitative order: Thr greater than Ser greater than Glx = Pro; in the antrum: Thr greater than Ser greater than Glx; and in the duodenum: Thr greater than Ser greater than Pro. Corpus, antral and duodenal mucus glycoproteins have the blood-group A antigen; antral mucus glycoprotein in particular exhibited strong blood-group A activity.

摘要

与胃体、胃窦和十二指肠相比,黏液糖蛋白的密度分别为1.52、1.49和1.57克/毫升。胃肠道黏液糖蛋白的碳水化合物组成包括N-乙酰半乳糖胺、N-乙酰葡糖胺、半乳糖、岩藻糖和唾液酸。胃体、胃窦和十二指肠黏液糖蛋白的碳水化合物组成比例不同。发现寡糖的平均长度在胃体、胃窦和十二指肠中分别约为12 - 13、14和10个糖。在胃体中,氨基酸含量具有以下定量顺序:苏氨酸>丝氨酸>谷氨酰胺 = 脯氨酸;在胃窦中:苏氨酸>丝氨酸>谷氨酰胺;在十二指肠中:苏氨酸>丝氨酸>脯氨酸。胃体、胃窦和十二指肠黏液糖蛋白具有A血型抗原;特别是胃窦黏液糖蛋白表现出较强的A血型活性。

相似文献

1
Comparative study on mucus glycoproteins in rat stomach and duodenum.大鼠胃和十二指肠黏液糖蛋白的比较研究
Comp Biochem Physiol B. 1986;83(2):273-5. doi: 10.1016/0305-0491(86)90365-2.
2
Two types of rat gastric mucus glycoprotein subunits.两种大鼠胃黏液糖蛋白亚基。
J Biochem. 1988 Jun;103(6):1050-3. doi: 10.1093/oxfordjournals.jbchem.a122378.
3
Comparative study on rat enteromucins.大鼠肠黏蛋白的比较研究
Comp Biochem Physiol B. 1993 Sep;106(1):147-52. doi: 10.1016/0305-0491(93)90020-6.
4
Gastric mucus glycoprotein in different rat strains.不同大鼠品系中的胃黏液糖蛋白
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1986;84(2):359-61. doi: 10.1016/0742-8413(86)90105-2.
5
Types of oligosaccharide sulphation, depending on mucus glycoprotein source, corpus or antral, in rat stomach.大鼠胃中寡糖硫酸化的类型,取决于黏液糖蛋白来源,即胃体或胃窦。
Biochem J. 1989 Dec 15;264(3):805-12. doi: 10.1042/bj2640805.
6
Structure of intestinal-mucus glycoprotein from human post-mortem or surgical tissue: inferences from correlation analyses of sugar and sulfate composition of individual mucins.来自人类尸检或手术组织的肠道黏液糖蛋白结构:基于单个黏蛋白糖和硫酸盐组成相关性分析的推断
Carbohydr Res. 1983 Apr 16;115:151-63. doi: 10.1016/0008-6215(83)88143-9.
7
Human duodenal gland (Brunner's gland) mucus glycoprotein analysis.人十二指肠腺(布伦纳腺)黏液糖蛋白分析。
Arch Biochem Biophys. 1984 Jan;228(1):64-70. doi: 10.1016/0003-9861(84)90047-x.
8
Terminal alpha (1 leads to 4)-linked N-acetylglucosamine: a characteristic constituent of duodenal-gland mucous glycoproteins in rat and pig. A high-resolution 1H-NMR study.末端α(1→4)连接的N-乙酰葡糖胺:大鼠和猪十二指肠腺黏液糖蛋白的特征成分。一项高分辨率1H-NMR研究。
Biochim Biophys Acta. 1983 Sep 14;747(1-2):107-16. doi: 10.1016/0167-4838(83)90128-0.
9
Comparison of the mucus glycoproteins present in the different layers of rat gastric mucosa.
Comp Biochem Physiol B. 1993 Feb;104(2):315-9. doi: 10.1016/0305-0491(93)90374-e.
10
[Immuno-reactive somatostatin in acetic extracts of duodenal, antral and fundic biopsies (author's transl)].十二指肠、胃窦和胃底活检组织醋酸提取物中的免疫反应性生长抑素(作者译)
Ann Endocrinol (Paris). 1977 Mar-Apr;38(2):147-8.

引用本文的文献

1
Establishment of monoclonal antibodies against carbohydrate moiety of gastric mucins distributed in the different sites and layers of rat gastric mucosa.
Glycoconj J. 1996 Oct;13(5):857-64. doi: 10.1007/BF00702350.
2
Mechanisms for cytoprotection by vitamin U from ethanol-induced gastric mucosal damage in rats.
Dig Dis Sci. 1996 Jan;41(1):49-54. doi: 10.1007/BF02208583.
3
Types of oligosaccharide sulphation, depending on mucus glycoprotein source, corpus or antral, in rat stomach.大鼠胃中寡糖硫酸化的类型,取决于黏液糖蛋白来源,即胃体或胃窦。
Biochem J. 1989 Dec 15;264(3):805-12. doi: 10.1042/bj2640805.