新制癌菌素：非蛋白质发色团的光谱表征与分离 - Suppr

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Neocarzinostatin: spectral characterization and separation of a non-protein chromophore.

作者信息

Napier M A, Holmquist B, Strydom D J, Goldberg I H

出版信息

Biochem Biophys Res Commun. 1979 Jul 27;89(2):635-42. doi: 10.1016/0006-291x(79)90677-6.

DOI:10.1016/0006-291x(79)90677-6

PMID:39562

Abstract

摘要

相似文献

Neocarzinostatin: spectral characterization and separation of a non-protein chromophore.新制癌菌素：非蛋白质发色团的光谱表征与分离

Biochem Biophys Res Commun. 1979 Jul 27;89(2):635-42. doi: 10.1016/0006-291x(79)90677-6.

Neocarzinostatin chromophore: purification of the major active form and characterization of its spectral and biological properties.新制癌菌素发色团：主要活性形式的纯化及其光谱和生物学性质的表征

Biochemistry. 1981 Sep 15;20(19):5602-8. doi: 10.1021/bi00522a038.

Effect of nonprotein chromophore removal on neocarzinostatin action.去除非蛋白质发色团对新制癌菌素作用的影响。

Biochemistry. 1980 Apr 29;19(9):1767-73. doi: 10.1021/bi00550a007.

Solution structure of a novel chromoprotein derived from apo-neocarzinostatin and a synthetic chromophore.源自脱辅基新制癌菌素和合成发色团的新型色蛋白的溶液结构

Biochemistry. 2002 Oct 1;41(39):11731-9. doi: 10.1021/bi0262146.

Neocarzinostatin chromophore. Assignment of spectral properties and structural requirements for binding to DNA.新制癌菌素发色团。光谱性质的归属及与DNA结合的结构要求

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The generalization of pre-neocarzinostatin and antagonism of neocarzinostatin-induced DNA scission in vitro.

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Neocarzinostatin: chemical characterization and partial structure of the non-protein chromophore.新制癌菌素：非蛋白质发色团的化学表征及部分结构

Biochem Biophys Res Commun. 1980 Aug 14;95(3):1351-6. doi: 10.1016/0006-291x(80)91622-8.

Role of epoxide in neocarzinostatin chromophore stability and action.环氧化物在新制癌菌素发色团稳定性及作用中的作用。

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Chromatographic and spectroscopic assignment of thiol induced cycloaromatizations of enediyne in neocarzinostatin.

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Neocarzinostatin: carboxyl-terminal-43-peptide residue of apo-neocarzinostatin as the binding site of neocarzinostatin-chromophore.新制癌菌素：脱辅基新制癌菌素的羧基末端43肽残基作为新制癌菌素发色团的结合位点。

Chem Pharm Bull (Tokyo). 1986 Dec;34(12):5180-3.

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Evaluating the use of Apo-neocarzinostatin as a cell penetrating protein.评估 Apo-neocarzinostatin 作为细胞穿透蛋白的用途。

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Identification of thymidine-5'-aldehyde at DNA strand breaks induced by neocarzinostatin chromophore.鉴定新制癌菌素生色团诱导的 DNA 链断裂中的胸苷-5'-醛。

Proc Natl Acad Sci U S A. 1982 Feb;79(3):744-8. doi: 10.1073/pnas.79.3.744.

Cold instability of aponeocarzinostatin and its stabilization by labile chromophore.阿波霉素的冷不稳定性及其由不稳定发色团实现的稳定化

Biophys J. 2005 Jun;88(6):4252-61. doi: 10.1529/biophysj.104.051722. Epub 2005 Apr 8.

Gene transcription analysis of Saccharomyces cerevisiae exposed to neocarzinostatin protein-chromophore complex reveals evidence of DNA damage, a potential mechanism of resistance, and consequences of prolonged exposure.暴露于新制癌菌素蛋白-发色团复合物的酿酒酵母基因转录分析揭示了DNA损伤的证据、一种潜在的抗性机制以及长期暴露的后果。

Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11075-80. doi: 10.1073/pnas.191340698. Epub 2001 Sep 18.

The role of monoclonal antibody A7 as a drug modifier in cancer therapy.单克隆抗体A7作为癌症治疗中药物修饰剂的作用。

Cancer Immunol Immunother. 1993;36(3):177-84. doi: 10.1007/BF01741089.

Production, binding and cytotoxicity of human/mouse chimeric monoclonal antibody-neocarzinostatin conjugate.人/鼠嵌合单克隆抗体-新制癌菌素缀合物的制备、结合及细胞毒性

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DNA breakage activity of the methanol extract of auromomycin.金霉素甲醇提取物的DNA断裂活性。

Cancer Chemother Pharmacol. 1981;7(1):41-50. doi: 10.1007/BF00258212.

Roles of chromophore and apo-protein in neocarzinostatin action.发色团和脱辅基蛋白在新制癌菌素作用中的角色。

Proc Natl Acad Sci U S A. 1980 Apr;77(4):1970-4. doi: 10.1073/pnas.77.4.1970.

Activation of neocarzinostatin chromophore and formation of nascent DNA damage do not require molecular oxygen.新制癌菌素生色团的激活和新生DNA损伤的形成不需要分子氧。

Nucleic Acids Res. 1985 Mar 11;13(5):1637-48. doi: 10.1093/nar/13.5.1637.

A tentative model of the intercalative binding of the neocarzinostatin chromophore to double-stranded tetranucleotides.新制癌菌素发色团与双链四核苷酸嵌入结合的初步模型。

Nucleic Acids Res. 1987 Mar 11;15(5):2175-89. doi: 10.1093/nar/15.5.2175.

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