Frauenfelder Giulia, Diana Francesco, Saponiero Renato, Romano Daniele Giuseppe
Department of Neuroradiology, A.O.U. San Giovanni di Dio e Ruggi d'Aragona, Salerno, Italy.
Department of Neuroradiology, University Hospital Vall d'Hebron, Barcelona, Spain.
Neuroradiol J. 2025 Jun;38(3):291-298. doi: 10.1177/19714009241303063. Epub 2024 Nov 19.
To date, the use of the most suitable first-pass technique for Mechanical Thrombectomy is still debated. In last years, several observational studies have suggested noninferiority or superiority of A Direct Aspiration first-Pass Technique (ADAPT) technique to achieve better reperfusion in comparison to stent retriever. While ASA/AHA 2018 guidelines recommend that patients with AIS should receive Mechanical Thrombectomy with a stent retriever, last European Stroke Organization guidelines report no evidence that stent retriever compared with contact aspiration could improve reperfusion rate. ADAPT is based on aspiration alone as the primary mechanism of thrombectomy and, if initially unsuccessful, then incorporating adjunctive alternatives. ADAPT improvement is also related to last generation of aspiration catheters. The purpose of this review is to report ADAPT principles, technique, efficacy, and safety as first-line treatment for acute ischemic stroke with the latest generation of reperfusion devices.
迄今为止,对于机械取栓最合适的首次通过技术的使用仍存在争议。在过去几年中,多项观察性研究表明,与支架取栓器相比,直接抽吸首次通过技术(ADAPT)在实现更好的再灌注方面具有非劣效性或优越性。虽然美国心脏协会/美国卒中协会(ASA/AHA)2018年指南建议急性缺血性卒中(AIS)患者应使用支架取栓器进行机械取栓,但欧洲卒中组织最新指南报告称,没有证据表明支架取栓器与接触抽吸相比能提高再灌注率。ADAPT仅基于抽吸作为取栓的主要机制,如果最初不成功,则采用辅助替代方法。ADAPT的改进也与新一代抽吸导管有关。本综述的目的是报告ADAPT作为急性缺血性卒中一线治疗的原理、技术、疗效和安全性,采用的是最新一代再灌注装置。